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Imaging of high-intensity focused ultrasound-induced lesions in soft biological tissue using thermoacoustic tomography
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10.1118/1.1829403
/content/aapm/journal/medphys/32/1/10.1118/1.1829403
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/32/1/10.1118/1.1829403
View: Figures

Figures

Image of FIG. 1.
FIG. 1.

Side view of the experimental setup.

Image of FIG. 2.
FIG. 2.

(a) Gross pathologic photograph of the sample used in the experiment. (b) Reconstructed image using the local-tomography-type algorithm. (c) Reconstructed image using the approximate filtered backprojection algorithm. The lesion region is indicated by arrows.

Image of FIG. 3.
FIG. 3.

(a) Photograph of the phantom used in the experiment. (b) Reconstructed image using local-tomography-type method.

Image of FIG. 4.
FIG. 4.

(a) Gross pathologic photograph of the sample used in the experiment; the lesion was induced at a radio frequency power of 15 W for one and one half minutes. (b) Schematic side view of the sample. Reconstructed image using local-tomography-type reconstruction method: (c) before heating; (d) after heating. (e) The differential image obtained by subtracting the data collected before heating from the data collected after heating. The lesion regions are indicated by dashed circles.

Image of FIG. 5.
FIG. 5.

Scatter plot of the area of the lesion evaluated using TAT versus the area measured from pathologic photographs. The evaluation was applied to ten lesions; the regression equation obtained using the weighted LS regression was .

Image of FIG. 6.
FIG. 6.

Simulation of a piezoelectric signal in response to a microwave-induced thermoacoustic signal. (a) The temporal profile of the impulse response of the 2.25 MHz transducer. (b) Spectrum of the 2.25 MHz ultrasonic transducer. (c) Temporal profile of the microwave pulse used in the simulations. (d) Thermoacoustic signals induced by an ideal microwave pulse for a sample with a low microwave absorption region in the center. (e) Thermoacoustic signals induced by microwave pulses used in the experiments for the same samples used in (d). (f) Simulated piezoelectric signals of the 2.25 MHz ultrasonic transducer for (e).

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/content/aapm/journal/medphys/32/1/10.1118/1.1829403
2004-12-10
2014-04-18
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Imaging of high-intensity focused ultrasound-induced lesions in soft biological tissue using thermoacoustic tomography
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/32/1/10.1118/1.1829403
10.1118/1.1829403
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