1887
banner image
No data available.
Please log in to see this content.
You have no subscription access to this content.
No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
Feasibility study of helical tomotherapy for total body or total marrow irradiationa)
a)This work was initiated at the University of Wisconsin, Madison.
Rent:
Rent this article for
USD
10.1118/1.2044428
    + View Affiliations - Hide Affiliations
    Affiliations:
    1 Department of Therapeutic Radiology, University of Minnesota, Minneapolis, 420 Delaware Street SE, Minneapolis, Minnesota 55455
    2 and Departments of Human Oncology, University of Wisconsin—Madison, 600 Highland Avenue, Madison, Wisconsin 53792
    3 Tomotherapy Incorporated, 1240 Deming Way, Madison, Wisconsin 53717
    4 Departments of Human Oncology, University of Wisconsin—Madison, 600 Highland Avenue, Madison, Wisconsin 53792
    5 Tomotherapy Incorporated, 1240 Deming Way, Madison, Wisconsin 53717
    6 Departments of Human Oncology, University of Wisconsin—Madison, 600 Highland Avenue, Madison, Wisconsin 53792
    7 Department of Therapeutic Radiology, University of Minnesota, Minneapolis, 420 Delaware Street SE, Minneapolis, Minnesota 55455
    8 Tomotherapy Incorporated, 1240 Deming Way, Madison, Wisconsin 53717 and Departments of Human Oncology, University of Wisconsin—Madison, 600 Highland Avenue, Madison, Wisconsin 53792
    9 Departments of Human Oncology, University of Wisconsin—Madison, 600 Highland Avenue, Madison, Wisconsin 53792
    b) Address for correspondence: Susanta K. Hui, Department of Therapeutic Radiology, University of Minnesota, 420 Delaware Street SE, Mayo Mail Code 494, Minneapolis, Minnesota 55455. Phone: 612-626-4484; fax: 612-626-7060; electronic mail: huixx019@umn.edu
    Med. Phys. 32, 3214 (2005); http://dx.doi.org/10.1118/1.2044428
/content/aapm/journal/medphys/32/10/10.1118/1.2044428
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/32/10/10.1118/1.2044428

Figures

Image of FIG. 1.
FIG. 1.

Anthromorphic Rando phantom placed on a Vac-Lok bag as a part of treatment and imaging procedures. A point in the phantom is aligned at the virtual isocenter, which is located outside the bore of the gantry. The coordinate system is shown in the upper left corner. The gantry has its covers removed.

Image of FIG. 2.
FIG. 2.

Isodose distribution shown on a patient CT, as calculated by the tomotherapy treatment planning. The left-side [(A), (B), (C), (D)] panel shows the planning dose distribution for total body irradiation. The right-side [(E), (F), (G)] shows the planning dose distribution for total bone marrow irradiation. Planning was done with a field width.

Image of FIG. 3.
FIG. 3.

Dose volume histogram for total body irradiation plan. Planning was done with field width.

Image of FIG. 4.
FIG. 4.

The effect of field width (J), MF, and pitch (P) on DVH for total body irradiation shown from left to right, respectively. The dose scale is drawn from to amplify the DVH variations with J, MF, and P.

Image of FIG. 5.
FIG. 5.

Dose volume histogram for the total marrow irradiation plan. Planning was done with a field width. The marrow target included a margin.

Image of FIG. 6.
FIG. 6.

Dose volume histogram for a total marrow target using the and field width, with and without a margin. Higher conformality is obtained with the field width.

Image of FIG. 7.
FIG. 7.

Bar chart shown for bone target and critical organs—lungs, eyes, heart, kidneys, and liver. Four bars in each group represents the average dose for 2.5 and field width for bone marrow only and bone marrow margin with standard deviation as an uncertainty.

Image of FIG. 8.
FIG. 8.

(A) Whole body MVCT, treatment planning kVCT, and fused images in a coronal view. (B) Limited MVCT at the level of (I) head, (II) chest, and (III) pelvis; treatment planning kVCT; and fused images in a coronal view. The saggital sectional view is shown in (C) and (D), and the transverse sectional view is shown in (E) and (F). For each panel, the fusion column presents the kVCT in gray scale with the MVCT superimposed with a level of transparency in yellow.

Tables

Generic image for table
TABLE I.

Average dose coverage (for total 8 fractions, ) for different organs with variations in field width (MF 2.0 and pitch 0.46).

Generic image for table
TABLE II.

Average dose coverage (for total 8 fraction, ) and impact of MF on the average dose in various OARs and target (field width and pitch 0.46).

Generic image for table
TABLE III.

Average dose coverage (for total 8 fraction, ) and impact of pitch on average dose in various OARs and target (field width and MF 3.0). Note: means reduction and means increment in percentage mean dose in eight fractions.

Generic image for table
TABLE IV.

A comparison of the lateral (Tx), longitudinal (Ty), and vertical (Tz) (IEC nomenclature) and roll offsets resulting from fusion for the average of the limited MVCT (fifth row) and whole body MVCT (last row). The uncertainties for the average values were obtained by adding the individual uncertainties in quadrature.

Generic image for table
TABLE V.

Doses measured with TLD compared to prescribed doses at the selected points in the rando phantom irradiated with helical tomotherapy for a single fraction . The uncertainty in TLD reading (radiation dose measurement) was 5%.

Loading

Article metrics loading...

/content/aapm/journal/medphys/32/10/10.1118/1.2044428
2005-09-29
2014-04-25
Loading

Full text loading...

This is a required field
Please enter a valid email address
752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Feasibility study of helical tomotherapy for total body or total marrow irradiationa)
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/32/10/10.1118/1.2044428
10.1118/1.2044428
SEARCH_EXPAND_ITEM