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Boron neutron capture enhancement of fast neutron radiotherapy utilizing a moderated fast neutron beam
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10.1118/1.1861156
/content/aapm/journal/medphys/32/3/10.1118/1.1861156
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/32/3/10.1118/1.1861156

Figures

Image of FIG. 1.
FIG. 1.

Lineal energy spectra measured with the A-150 TEPC using a simulated site diameter of 1 μm in the (a) unmoderated and (b) moderated FNT beams at a depth of 2.5 cm in water separated into their respective gamma and neutron components.

Image of FIG. 2.
FIG. 2.

Changes in the moderated BNCEFNT beam spectrum as a function of depth as measured using the the A-150 TEPC.

Image of FIG. 3.
FIG. 3.

Lineal energy spectra measured with the A-150 and -loaded A-150 TEPCs in the moderated beam at a depth of 2.5 cm in water using a simulated site diameter of 1 μm.

Image of FIG. 4.
FIG. 4.

Thermal neutron fluence as a function of depth in water in the moderated beam. The point measurements were obtained from TEPC measurements, while the paired Mg ionization chambers were used to obtain the scanned data.

Image of FIG. 5.
FIG. 5.

Crossplane profile of relative thermal neutron fluence in the moderated beam using a field size at a depth of 5 cm in water.

Image of FIG. 6.
FIG. 6.

Neutron components of the lineal energy spectra measured at a depth of 2.5 cm in water in both the moderated BNECFNT beam and unmoderated clinical fast neutron beam using a simulated site diameter of 1 μm. Also shown in the biological weighting function developed by Loncol et al. (Ref. 49).

Tables

Generic image for table
TABLE I.

RBE-weighted absorbed doses in cGy per monitor unit extracted from the TEPC measurements shown in Fig. 2 (The current configuration allows delivery of approximately 40 MU∕min.) Boron-10 concentrations of 15 and 55 μg∕g were assumed for normal brain and tumor, respectively. RBE values of 1 and 3.2 are used for the gamma and neutron components, and cRBE values of 1.35 and 3.8 are used for the BNC components in normal brain and tumor, respectively.

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/content/aapm/journal/medphys/32/3/10.1118/1.1861156
2005-02-16
2014-04-16
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Boron neutron capture enhancement of fast neutron radiotherapy utilizing a moderated fast neutron beam
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/32/3/10.1118/1.1861156
10.1118/1.1861156
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