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SemiSPECT: A small-animal single-photon emission computed tomography (SPECT) imager based on eight cadmium zinc telluride (CZT) detector arrays
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10.1118/1.2164070
/content/aapm/journal/medphys/33/2/10.1118/1.2164070
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/33/2/10.1118/1.2164070
View: Figures

Figures

Image of FIG. 1.
FIG. 1.

Block diagram of a list-mode data acquisition board.

Image of FIG. 2.
FIG. 2.

Photographs of outside (a) and inside (b) views of SemiSPECT.

Image of FIG. 3.
FIG. 3.

Normalized of SemiSPECT along (graph a), (graph b), and (graph c) axes, where the axis is perpendicular to the circular slices of the cylindrical object space. On each graph, the dots represent the values of the , and the line represents a Gaussian function closest to the . The deviation from the Gaussian at high spatial frequencies is caused by using the discrete Fourier transform rather than the Fourier integral required in the definition.

Image of FIG. 4.
FIG. 4.

energy spectrum for interactions in an group of pixels at the center region of a detector; except for statistics, essentially the same spectrum is obtained if a larger or smaller region is used. The bump near is caused by K x rays created from the gold insert on the cylinder aperture or lead and bismuth contained in the Cerrobend of the cylinder aperture when gamma rays interacted in them. The energy resolution is about 10% as measured by full-width-at-half-maximum of the photopeak .

Image of FIG. 5.
FIG. 5.

Sensitivity map of SemiSPECT. The straight dark lines indicated by black arrows were caused by detector regions having less sensitivity.

Image of FIG. 6.
FIG. 6.

Diagram (a) shows the geometry of a line phantom; group (a) includes three holes with diameter and center-to-center distance, group (b) includes 5 holes with diameter and center-to-center distance, and group (c) includes 10 holes with diameter and center-to-center distance. The SPECT images of the line phantom are presented in (b) with separation between neighboring slices.

Image of FIG. 7.
FIG. 7.

Volume rendering (a) from the SPECT images of a whole mouse skeleton and consecutive transaxial SPECT images of (bB) the mouse cranium from incisive bone to occipital squama, and (c) the mouse pelvic bone from ilium to ischiac bone with separation between slices. -MDP was used as the bone imaging agent.

Image of FIG. 8.
FIG. 8.

(a) Volume rendering from the SPECT images of a mouse myocardium, and (b) consecutive transaxial SPECT slices of it with separation between slices. -MIBI was used as the imaging agent.

Image of FIG. 9.
FIG. 9.

(a) Photograph of a mouse bearing a human-breast-tumor xenograft, (b) volume rendering from the SPECT images of it, and (c) consecutive transaxial SPECT images of the tumor indicated by a black dotted circle with separation between slices. -glucarate was used as the tumor imaging agent.

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/content/aapm/journal/medphys/33/2/10.1118/1.2164070
2006-01-30
2014-04-21
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: SemiSPECT: A small-animal single-photon emission computed tomography (SPECT) imager based on eight cadmium zinc telluride (CZT) detector arrays
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/33/2/10.1118/1.2164070
10.1118/1.2164070
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