1887
banner image
No data available.
Please log in to see this content.
You have no subscription access to this content.
No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
Determination of the prescription dose for biradionuclide permanent prostate brachytherapy
Rent:
Rent this article for
USD
10.1118/1.3002417
/content/aapm/journal/medphys/35/12/10.1118/1.3002417
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/35/12/10.1118/1.3002417

Figures

Image of FIG. 1.
FIG. 1.

Relative dose distribution, i.e., ratio of dose and prescription dose, as a function of distance for , , and seeds used for monoradionuclide implants. Two loading patterns (LPs) are considered: The and the . The loading pattern is supposed to be the same as the . The thick curves correspond to the seeds distributed with their own loading pattern (i.e., seeds with loading pattern and or seeds with the loading pattern). The thin curves correspond to the other loading pattern (i.e., seeds with loading pattern and or seeds with the loading pattern).

Image of FIG. 2.
FIG. 2.

Radial dose function of the mono- and biradionuclide seeds. Physical parameters are from Table I.

Image of FIG. 3.
FIG. 3.

Survival fractions obtained for a prostate implanted with InterSource loaded with , , or . Edema magnitude and half-life . Biological parameters: Set 1. Effect of RBE: : 1.41, : 1.28, : 1.28 (thick); or : 1, : 1, : 1 (thin). Vertical lines: Prescription doses.

Image of FIG. 4.
FIG. 4.

Isosurvival fractions (thin) obtained for a prostate implant with InterSource loaded with a mixture of 75% of the internal activities coming from and 25% from . The activity-dose relationship (thick) gives the dose delivered by each radionuclide for increasing total initial activity. Edema magnitude and half-life . Biological parameters: Set 1. RBE: : 1.41 and : 1.28.

Image of FIG. 5.
FIG. 5.

Isosurvival fractions obtained for a prostate implant with InterSource loaded with a mixture of 25% of the internal activities coming from and 75% from . The activity-dose relationship (thick) gives the dose delivered by each radionuclide for increasing total initial activity. Edema magnitude and half-life . Biological parameters: Set 1. RBE: : 1.41 and : 1.28.

Image of FIG. 6.
FIG. 6.

Computed prescription dose for the as a function of the edema magnitude for different edema half-life by considering a implant (solid) or a implant (dash) as a benchmark. The first parameter set was used. The RBE for and were assumed to be 1.41 and 1.28, respectively.

Image of FIG. 7.
FIG. 7.

Computed prescription dose for the as a function of the edema magnitude for different edema half-life by considering a implant (solid) or a implant (dot) as a benchmark. The first parameter set was used. The RBE for and were assumed to be 1.41 and 1.28, respectively.

Image of FIG. 8.
FIG. 8.

Computed prescription dose for the as a function of the edema magnitude for the first (filled square), the second (empty triangle), and the third set of biological parameters (half-filled circle) by considering a implant (solid) or a implant (dash) as a benchmark. An edema half-life of was used. RBE effect was ignored.

Image of FIG. 9.
FIG. 9.

Computed prescription dose for the as a function of the edema magnitude for the first (filled square), the second (empty triangle), and the third set of biological parameters (half-filled circle) by considering a implant (solid) or a implant (dot) as a benchmark. An edema half-life of was used. RBE effect was ignored.

Image of FIG. 10.
FIG. 10.

Computed prescription dose for the as a function of the edema magnitude for different RBE values by considering a implant (solid) or a implant (dash) as a benchmark. The first parameter set was used. An edema half-life of was used.

Image of FIG. 11.
FIG. 11.

Computed prescription dose for the as a function of the edema magnitude for different RBE values by considering a implant (solid) or a implant (dot) as a benchmark. The first parameter set was used. An edema half-life of was used.

Image of FIG. 12.
FIG. 12.

Effective dose as a function of edema magnitude normalized to its value at zero edema magnitude for different edema half-lives.

Tables

Generic image for table
TABLE I.

Physical parameters for the InterSource™ seeds. values are from Wang et al. (Ref. 15).

Generic image for table
TABLE II.

Biological parameters.

Loading

Article metrics loading...

/content/aapm/journal/medphys/35/12/10.1118/1.3002417
2008-11-12
2014-04-25
Loading

Full text loading...

This is a required field
Please enter a valid email address
752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Determination of the prescription dose for biradionuclide permanent prostate brachytherapy
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/35/12/10.1118/1.3002417
10.1118/1.3002417
SEARCH_EXPAND_ITEM