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Analytical optimization of digital subtraction mammography with contrast medium using a commercial unit
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10.1118/1.3003063
/content/aapm/journal/medphys/35/12/10.1118/1.3003063
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/35/12/10.1118/1.3003063

Figures

Image of FIG. 1.
FIG. 1.

Geometrical model for orthogonal hexahedra of length and square cross section of size . For a cylinder of diameter , can be assumed to be the mean chord value. and represent the iodine and water thickness within the tube.

Image of FIG. 2.
FIG. 2.

Nontemporal dual energy subtraction (DE) (a) contrast and (b) contrast noise values as function of image 1 equivalent energy, , for various spectral combinations, images 1 and 2 acquired with iodinated spectra. A 29% glandular, thick breast was considered, with a tube containing of iodine. Labels refer to image 2 x-ray spectra, using the identification system introduced in Table I.

Image of FIG. 3.
FIG. 3.

Temporal subtraction (a) contrast, and (b) contrast noise values as function of image 2 equivalent energy , for various spectral combinations. A 29% glandular, thick breast was considered, with a tube containing of iodine. Images 1 and 2 are acquired with the iodinated and the noniodinated spectra, respectively, resulting in positive contrast values. Labels refer to image 1 x-ray spectra, using the identification system introduced in Table I.

Image of FIG. 4.
FIG. 4.

Temporal subtraction (a) contrast, and (b) contrast noise values as function of image 1 equivalent energy , for various spectral combinations. A 29% glandular, thick breast was considered, with a tube containing of iodine. Absolute values of negative contrast are shown, with images 1 and 2 acquired with the noniodinated and the iodinated spectra, respectively. Labels refer to image 2 x-ray spectra, using the identification system introduced in Table I.

Image of FIG. 5.
FIG. 5.

CNR predictions in nontemporal dual energy subtraction (DE) as function of image 1 equivalent energy , for various spectral combinations. A 29% glandular, thick breast was considered, with a tube containing of iodine. Labels refer to image 2 spectra, using the identification system introduced in Table I.

Image of FIG. 6.
FIG. 6.

CNR predictions in temporal subtraction for various spectral combinations. A 29% glandular, thick breast was considered, with a tube containing of iodine. (a) CNR from positive contrast values as function of image 2 equivalent energy (images 1 and 2 acquired with the iodinated and the noniodinated spectra, respectively). (b) CNR from absolute values of negative contrast as function of image 1 equivalent energy (images 1 and 2 acquired with the noniodinated and the iodinated spectra, respectively). Labels refer to iodinated image x-ray spectra, using the identification system introduced in Table I.

Image of FIG. 7.
FIG. 7.

Total mean glandular dose for DE and DET modalities (solid) as function of image 1 equivalent energy (low-energy image in both modalities), considering equal distribution of total breast-entrance air kerma between both images. A 29% glandular, thick breast was assumed. Low-energy spectra: Mo34, Rh32, Rh34, Rh38, Rh45, Rh45H, and Rh45H2; fixed high-energy spectrum: Rh45H4. Also included, the SET value (dashed) when both images are acquired with the fixed high-energy spectrum. Labels indicate the subtraction modality pertaining to each curve.

Image of FIG. 8.
FIG. 8.

(a) Contrast and (b) CNR in subtracted images using the optimized radiological spectra (Rh34, Rh45H4) as function of iodine mass thickness, simulating a 29% glandular, thick breast containing various iodine concentrations (1, 2, 5, 9, 18, 37.5, 75, 150, and ) in a diameter tube. The total breast-entrance air kerma was equally distributed between both images. Labels indicate the subtraction modality pertaining to each curve.

Image of FIG. 9.
FIG. 9.

Predicted FOM values as function of image 1 relative breast-entrance air kerma for various subtraction modalities (DE, SET, and DET), assuming a diameter tube with , embedded in a 29% glandular, thick breast, and using the proposed spectra: Rh34 and Rh45H4. Labels indicate the subtraction modality pertaining to each curve.

Tables

Generic image for table
TABLE I.

Beam quality characteristics (identification, calculated half-value layer HVL in mm Al, normalized mean glandular dose , and equivalent energy ) for the simulated mammographic x-ray spectra.

Generic image for table
TABLE II.

Attenuation densities, their ratio, and their difference for background and iodine regions imaged with polyenergetic x-ray beams presented in Table I. The object of interest is a long, diameter tube, containing a iodine-based aqueous solution.

Generic image for table
TABLE III.

Proposed radiological parameters (spectral combination, relative breast-entrance air kerma , and iodine presence) for different subtraction modalities. Values of were obtained under total breast entrance air kerma of .

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/content/aapm/journal/medphys/35/12/10.1118/1.3003063
2008-11-14
2014-04-20
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Analytical optimization of digital subtraction mammography with contrast medium using a commercial unit
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/35/12/10.1118/1.3003063
10.1118/1.3003063
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