Skindose is one of the key issues for clinical dosimetry in radiation therapy. Currently planning computer systems are unable to accurately predict dose in the buildup region, leaving ambiguity as to the dose levels actually received by the patient’s skin during radiotherapy. This is one of the prime reasons why in vivo measurements are necessary to estimate the dose in the buildup region. A newly developed metal-oxide-semiconductor-field-effect-transistor (MOSFET)detector designed specifically for dose measurements in rapidly changing dose gradients was introduced for accurate in vivoskindosimetry. The feasibility of this detector for skindose measurements was verified in comparison with plane parallel ionization chamber and radiochromic films. The accuracy of a commercial treatment planning system (TPS) in skindose calculations for intensity-modulated radiation therapy treatment of nasopharyngeal carcinoma was evaluated using MOSFETdetectors in an anthropomorphic phantom as well as on the patients. Results show that this newly developed MOSFETdetector can provide a minimal but highly reproducible intrinsic buildup of corresponding to the requirements of personal surface dose equivalent Hp (0.07). The reproducibility of the MOSFET response, in high sensitivity mode, is found to be better than 2% at the phantom surface for the doses normally delivered to the patients. The MOSFETdetector agrees well with the Attix chamber and the EBT Gafchromic® film in terms of surface and buildup region dose measurements, even for oblique incident beams. While the dose difference between MOSFET measurements and TPS calculations is within measurement uncertainty for the depths equal to or greater than , an overestimation of up to 8.5% was found for the surface dose calculations in the anthropomorphic phantom study. In vivoskindose measurements reveal that the dose difference between the MOSFET results and the TPS calculations was on average , ranging from to . The newly designed MOSFETdetector encapsulated into a thin water protective film has a minimal reproducible intrinsic buildup recommended for skindosimetry. This feature makes it very suitable for routine IMRT QA and accurate in vivoskindosimetry.
II. MATERIALS AND METHODS
II.A. Phantom and irradiation conditions
II.B. MOSFETdosimetry system
II.C. Comparison of surface and build-up region dose measurements
II.C.1. Reference ionization chamberdosimetry
II.C.2. Film dosimetry
II.D. Evaluation of a commercial treatment planning system for surface and buildup region dose calculations
II.D.1. Anthropomorphic phantom and CT simulation
II.D.2. Treatment planning
II.D.3. Surface and buildup region dose measurements
II.E. In vivo measurement of patient skindose
III.A. Comparison of surface and buildup region dose measurements
III.B. Evaluation of a commercial treatment planning system for surface and buildup region dose calculations
III.C. In vivo measurement of patient skindose
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