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Tomosynthesis imaging: At a translational crossroads
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a decades-old technique for section imaging that has seen a recent upsurge
in interest due to its promise to provide three-dimensional information at lower
potentially lower cost than CT in certain clinical imaging situations. This renewed
interest in tomosynthesis began in the late 1990s as a new generation of flat-panel
available; these detectors were the one missing piece of the picture that had kept
from enjoying significant utilization earlier. In the past decade, tomosynthesisimaging has been investigated in a variety of clinical imaging
situations, but the two most prominent have been in breast and chest imaging.Tomosynthesis has
the potential to substantially change the way in which breast cancer and pulmonary nodules
are detected and
managed. Commercial tomosynthesis devices are now available or on the horizon. Many of the
remaining research activities with tomosynthesis will be translational in nature and will involve
physicist and clinician alike. This overview article provides a forward-looking assessment
of the translational questions facing tomosynthesisimaging and anticipates some of the likely research and clinical
activities in the next five years.
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