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Monte Carlo model for a prototype CT-compatible, anatomically adaptive, shielded intracavitary brachytherapy applicator for the treatment of cervical cancer
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10.1118/1.3193682
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    Affiliations:
    1 Department of Radiation Physics, The University of Texas M. D. Anderson Cancer Center, 1220 Holcombe Boulevard, Houston, Texas 77030 and Graduate School of Biomedical Sciences, The University of Texas–Houston, 6767 Bertner Avenue, Houston, Texas 77030
    2 Department of Radiation Physics, The University of Texas M. D. Anderson Cancer Center, 1220 Holcombe Boulevard, Houston, Texas 77030
    3 Division of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, 1220 Holcombe Boulevard, Houston, Texas 77030 and Graduate School of Biomedical Sciences, The University of Texas–Houston, 6767 Bertner Avenue, Houston, Texas 77030
    4 Department of Radiation Physics, The University of Texas M. D. Anderson Cancer Center, 1220 Holcombe Boulevard, Houston, Texas 77030 and Graduate School of Biomedical Sciences, The University of Texas–Houston, 6767 Bertner Avenue, Houston, Texas 77030
    5 Department of Radiation Physics, The University of Texas M. D. Anderson Cancer Center, 1220 Holcombe Boulevard, Houston, Texas 77030
    6 Department of Radiation Physics, The University of Texas M. D. Anderson Cancer Center, 1220 Holcombe Boulevard, Houston, Texas 77030 and Graduate School of Biomedical Sciences, The University of Texas–Houston, 6767 Bertner Avenue, Houston, Texas 77030
    a) Electronic mail: mprice@marybird.com; Current address: Mary Bird Perkins Cancer Center, 4950 Essen Lane, Baton Rouge, LA 70809 and Department of Physics and Astronomy, Louisiana State University, 202 Nicholson Hall, Tower Drive, Baton Rouge, Louisiana 70803.
    Med. Phys. 36, 4147 (2009); http://dx.doi.org/10.1118/1.3193682
/content/aapm/journal/medphys/36/9/10.1118/1.3193682
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/36/9/10.1118/1.3193682

Figures

Image of FIG. 1.
FIG. 1.

Comparison of CT images acquired in planes passing through the bladder and rectal shields of a single sFSD and sFW ovoid, as well as the corresponding planes for an ovoid inserted within a phantom that positions the ovoids in a clinically relevant orientation.

Image of FIG. 2.
FIG. 2.

Photograph of the ovoid used in this study. Quarter included for scale comparison.

Image of FIG. 3.
FIG. 3.

Internal components of the ovoid. Major components labeled: (a) Movable shield, (b) shield carrier, (c) distal stop pins, (d) shield retainers, (e) threaded shaft (tread detail omitted), (f) proximal stop, (g) pinion gear assembly, (h) outer rotating sleeve, (i) flexible drive wire, and (j) proximal shield stop pin. The polysulfone cap that surrounds the ovoid is not shown.

Image of FIG. 4.
FIG. 4.

Radiographs of the ovoid used to verify shield/source position for MC model validation. For all radiographs, the source is positioned at the center of the ovoid long axis. Images 1(a) and 1(b) show the ’s movable shield in its most distal position in a view perpendicular and parallel to the ovoid long axis, respectively. Similarly, images 2(a) and (b) and 3(a) and (b) present these views with the ’s movable shield in a position at the midpoint of the ovoid and a proximal position with respect to the source, respectively. The dashed line denotes the plane in which film measurements were performed.

Image of FIG. 5.
FIG. 5.

Two-dimensional plots of the ovoid using the MCNPX graphical plotter through (a) the -plane bisecting the ovoid shaft, (b) the -plane bisecting the movable shield in its most distal position, and (c) the -plane bisecting the ovoid shaft. The mHDR v2 source is shown in its most distal position and is unlabeled. Alphabetically labeled components: (a) Shield retainers, (b) threaded shaft, (c) ovoid shaft, (d) proximal shield stop pin, (e) distal stop pin, and (f) proximal stop pin.

Image of FIG. 6.
FIG. 6.

Medial plane absolute dose results (isodose contours shown in units of Gy) for MD-55-2 radiochromic film for MC model validation, averaged from three films (solid line) and for the MCNPX Monte Carlo model (dashed line). The units of both axes are in mm. For this film exposure, the shield position (and film plane) is shown in Fig. 4 [1(a) and 1(b)].

Image of FIG. 7.
FIG. 7.

Medial plane absolute dose results (isodose contours shown in units of Gy) for MD-55-2 radiochromic film for MC model validation, averaged from two films (solid line) and for the MCNPX Monte Carlo model (dashed line). The units of both axes are in mm. For this film exposure, the shield’s position (and film plane) is shown in Fig. 4 [2(a) and 2(b)].

Image of FIG. 8.
FIG. 8.

Medial plane absolute dose results (isodose contours shown in units of Gy) for MD-55-2 radiochromic film for MC model validation, averaged from two films (solid line) and for the MCNPX Monte Carlo model (dashed line). The units of both axes are in mm. For this film exposure, the shield’s position (and film plane) is shown in Fig. 4 [3(a) and 3(b)].

Tables

Generic image for table
TABLE I.

Materials of structures used in the Monte Carlo simulations, their compositions by weight and density. Dry air is defined at sea level and .

Generic image for table
TABLE II.

Estimated relative uncertainties of the radiochromic film dose interpretations per measured unit reference air kerma rate.

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/content/aapm/journal/medphys/36/9/10.1118/1.3193682
2009-08-12
2014-04-23
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Monte Carlo model for a prototype CT-compatible, anatomically adaptive, shielded intracavitary brachytherapy applicator for the treatment of cervical cancer
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/36/9/10.1118/1.3193682
10.1118/1.3193682
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