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ACCOMP: Augmented cell competition algorithm for breast lesion demarcation in sonography
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10.1118/1.3512799
/content/aapm/journal/medphys/37/12/10.1118/1.3512799
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/37/12/10.1118/1.3512799

Figures

Image of FIG. 1.
FIG. 1.

Illustration of a decomposition of a breast lesion into prominent components. (a) An ROI of a sonography containing a benign breast lesion. (b) A decomposition of a breast lesion into prominent components. In (b), a region enclosed by dotted lines is regarded to be a prominent component.

Image of FIG. 2.
FIG. 2.

Tessellating a ROI into elementary cell, cell, and prominent component structures. (a) A ROI of a sonography. (b) Elementary cell tessellation by the first-pass watershed transformation. (c) Cell tessellation from the second-pass watershed transformation. (d) Prominent component tessellation by cell competition process.

Image of FIG. 3.
FIG. 3.

The transformation process of the edge structure of a prominent component tessellation into corresponding c-graph. (a) A prominent component tessellation of a benign lesion. (b) The corresponding c-graph. In (b), a cycle constituted of a set of sequential darker graph nodes may be regarded as the desired boundary of the breast lesion.

Image of FIG. 4.
FIG. 4.

Profiling the bilateral vicinities of a p-edgel. The bilateral profiles of the p-edgel can be obtained by morphological dilation with a specific size of structural element. is the profile of the left vicinity of the p-edgel while the right profile is .

Image of FIG. 5.
FIG. 5.

Two types of p-edgel. (a) and (b) demonstrate cliff p-edgels with different slope orientations. (c) indicates a peak type p-edgel. It can be found that cliff type of p-edgel holds significant altitude difference in bilateral vicinities.

Image of FIG. 6.
FIG. 6.

The inner lateral vicinities along a breast lesion boundary may appear darker than outer vicinities. and , , indicate outer and inner vicinities around the lesion boundary, respectively.

Image of FIG. 7.
FIG. 7.

Scenarios of depth-first search scheme to concatenate p-edgels. (a) Demonstrations of the desired and undesired combination of p-edgels. p-edgel can possibly go to p-edgels , , and . The combination of p-edgels and violates the slope consistence rule and is excluded in the c-graph searching. (b) The traversing orientation of a closed curve can be determined by the sign of overall turning angles, i.e., . In (a) and (b), and are vertices interconnecting the p-edgels.

Image of FIG. 8.
FIG. 8.

Boundary candidates proposed by ACCOMP algorithm for the benign lesion in Fig. 2. (a) Rough outline derived from the region competition algorithm. (b) The prominent component tessellation from the cell competition process. The initial p-edgel for the retrieval of cycles is indicated by the white dotted circle. [(c)–(g)] Five boundary candidates with respect to the five cost functions C1–C5. (h) A manual delineation confirmed by an experienced medical doctor.

Image of FIG. 9.
FIG. 9.

Flow chart of the ACCOMP algorithm. The left column illustrates the major steps of the proposed algorithm. The right column diagrams the processes of cell-based contour grouping.

Image of FIG. 10.
FIG. 10.

Comparison of the manual delineations and the boundaries generated by ACCOMP, thresholding-based, and level-set-based algorithms for a breast malignant lesion. The image in the first row is the ROI of the original sonography, while the images in the second, third, fourth, and fifth rows report the manual delineations and the boundaries generated by ACCOMP, thresholding-based, and level-set-based algorithms, respectively.

Tables

Generic image for table

Algorithm 1

Generic image for table
TABLE I.

Four metrics, including the modified Williams index, percentage statistic, overlapping ratio, and difference ratio, for evaluation of the quality of the computer-generated boundaries with respect to the manually delineated boundaries.

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/content/aapm/journal/medphys/37/12/10.1118/1.3512799
2010-11-12
2014-04-23
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: ACCOMP: Augmented cell competition algorithm for breast lesion demarcation in sonography
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/37/12/10.1118/1.3512799
10.1118/1.3512799
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