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An improved model for describing the contrast bolus in perfusion MRI
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10.1118/1.3658570
/content/aapm/journal/medphys/38/12/10.1118/1.3658570
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/38/12/10.1118/1.3658570
View: Figures

Figures

Image of FIG. 1.
FIG. 1.

Diagram of a typical signal time curve illustrating how the last fitted point for the gamma variate was selected for each method: (i) third point after the bolus minimum, (ii) point of the half drop of the bolus after the bolus minimum, (iii) the point after the minimum at which the signal exceeds the post bolus signal minus the standard deviation of the pre bolus signal (σ) and (iv) by visual determination.

Image of FIG. 2.
FIG. 2.

Example of the bolus (solid line) and recirculation (dotted line) portions of the SCR model and bolus (dashed line) of a GV fitted to a typical concentration time curve (crosses).

Image of FIG. 3.
FIG. 3.

Fits (line) to concentration time curves (crosses). The left column gives the “noiseless” concentration time curves and the right has added noise to give an SNR of 25.

Image of FIG. 4.
FIG. 4.

Percent error (a) and percent deviation (b) of the AUC plotted against SNR for each model. Percent error (c) and percent deviation (d) of the FM plotted against SNR for each model.

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/content/aapm/journal/medphys/38/12/10.1118/1.3658570
2011-11-09
2014-04-23
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: An improved model for describing the contrast bolus in perfusion MRI
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/38/12/10.1118/1.3658570
10.1118/1.3658570
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