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Measurement of regional compliance using 4DCT images for assessment of radiation treatmenta)
a)Conflict of interest: None.
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10.1118/1.3555299
/content/aapm/journal/medphys/38/3/10.1118/1.3555299
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/38/3/10.1118/1.3555299

Figures

Image of FIG. 1.
FIG. 1.

The value calculated at the voxel is 0.5 in both pre- and post-treatments, while the voxel has different regional compliances. The images cannot show the RC difference at the voxel .

Image of FIG. 2.
FIG. 2.

(a) The reference image of the POPI-modeled patient. (b) The warped moving image of the POPI-modeled patient. (c) The difference image between the reference and the warped moving images. (d) The difference image between the reference and the original moving images. The images in (a) and (b) are displayed at the window and level of 500/180, and the images in (c) and (d) are at the window and level of 500/50.

Image of FIG. 3.
FIG. 3.

(a) A transversal slice of the reference image of the POPI-modeled patient with the tumor marked within the square box. (b) The Jacobian image of the Demons DVF.

Image of FIG. 4.
FIG. 4.

(a) and (b) are the transversal and coronal cuts of the stress image (kPa) of the POPI-modeled patient calculated from phase 1 to phase 5. (c) and (d) are the corresponding cuts of the stress image (kPa) calculated from phase 4 to phase 5.

Image of FIG. 5.
FIG. 5.

The residue errors of the elastic stress computed at (a) phase 1 and (b) phase 4.

Image of FIG. 6.
FIG. 6.

(a) and (b) are the transversal and coronal cuts of the ventilation image of the POPI-modeled patient calculated from phase 1 to phase 5. (c) and (d) are the corresponding cuts of the image calculated from phase 4 to phase 5.

Image of FIG. 7.
FIG. 7.

(a) and (b) are the transversal and coronal cuts of the RC image (1/kPa) calculated from phase 1 to phase 5 for the POPI-modeled patient. (c) and (d) are the corresponding cuts of the RC-image calculated from phase 4 to phase 5.

Image of FIG. 8.
FIG. 8.

The ventilation and compliance measured from the 4DCT images of the five patients treated in HFHS: (a) The average values, (b) the average stresses, (c) the average regional compliances, and (d) the average CT numbers in the lung.

Image of FIG. 9.
FIG. 9.

(a) the CT image of the first patient treated in HFHS; [(b)–(d)] the , stress, and regional compliance images; [(e)–(h)] the regional compliance images of the other four patients at the endinhalation phase and [(i)–(l)] the corresponding images at the midexhalation phase.

Image of FIG. 10.
FIG. 10.

The average elastic stress of the lung deformation of the POPI-modeled patient simulated with different elasticity parameters and with the displacements derived from the Demons registration from phase 1 to phase 5.

Image of FIG. 11.
FIG. 11.

(a), (b), and (c) represent a transversal cut of the stress images calculated with the parameters (a), (b), and (c), respectively.

Tables

Generic image for table
TABLE I.

The mean errors of the Demons registrations related to the measured landmark displacements.

Generic image for table
TABLE II.

The elastic stress and the associated errors for the deformation map from phase to phase 5 were computed using the registration-based biomechanical model.

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/content/aapm/journal/medphys/38/3/10.1118/1.3555299
2011-02-24
2014-04-18
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Measurement of regional compliance using 4DCT images for assessment of radiation treatmenta)
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/38/3/10.1118/1.3555299
10.1118/1.3555299
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