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Recommendations of the American Association of Physicists in Medicine on
dosimetry, imaging, and quality assurance procedures for 90Y microsphere
brachytherapy in the treatment of hepatic malignancies
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Yttrium-90 microsphere brachytherapy of the liver exploits the distinctive features of the
anatomy to treat
beta radiation and
is gaining more wide spread clinical use. This report provides a general overview of
assists the treatment team in creating local treatment practices to provide safe and
efficient patient treatment. Suggestions for future improvements are incorporated with the
basic rationale for the therapy and currently used procedures. Imaging modalities utilized and
their respective quality assurance are discussed. General as well as vendor specific
delivery procedures are reviewed. The current dosimetry models are reviewed and suggestions for
advancement are made. Beta activity standards are reviewed and vendor implementation
strategies are discussed. Radioactive material licensing and radiation safety are discussed
given the unique requirements of microsphere brachytherapy. A general, team-based quality assurance
program is reviewed to provide guidance for the creation of the local procedures. Finally,
recommendations are given on how to deliver the current state of the art treatments and
directions for future improvements in the therapy.
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