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Resolving axon fiber crossings at clinical b-values: An evaluation study
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10.1118/1.3626571
/content/aapm/journal/medphys/38/9/10.1118/1.3626571
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/38/9/10.1118/1.3626571

Figures

Image of FIG. 1.
FIG. 1.

Schema of fiber geometry for simulation of diffusion within and around impermeable cylinders. This particular example shows a θ = 30° crossing.

Image of FIG. 2.
FIG. 2.

Scheme of the error metrics for the evaluation of multifiber methods. Blue lines denote actual fiber orientations and actual compartment sizes (denoted by line length), red lines denote orientation and compartment size of a particular solution. All of the error metrics are defined so that a smaller number indicates a better solution.

Image of FIG. 3.
FIG. 3.

Results for free diffusion model synthetic signals. The actual compartment sizes are [0.5 0.5] for the two fiber crossings, and [0.33 0.33 0.33] for the three fiber crossing. Experiments in x axis correspond to configurations 230, 240, 250, 260, , and , respectively.

Image of FIG. 4.
FIG. 4.

Results for free diffusion model synthetic signals. The compartment sizes are [0.6 0.4] for two fiber crossings, and [0.4 0.3 0.3] for three fiber crossing.

Image of FIG. 5.
FIG. 5.

Results for free diffusion model synthetic signals. The compartment sizes are [0.7 0.3] for the two fiber crossings, and [0.50 0.25 0.25] for the three fiber crossings.

Image of FIG. 6.
FIG. 6.

Results for cylinder restricted diffusion model synthetic signals. The actual compartment sizes are [0.5 0.5] for our two fiber crossings. Experiments in x axis correspond to configurations 230, 240, 250, 260, and 290, respectively.

Image of FIG. 7.
FIG. 7.

Panels (e) and (f) show the plots of Error vs SNR (in x axis) with in vivo DW data for the ROIs in (a) and (b), respectively. We show in (c) and (d) the number of diffusion peaks (dark gray = 1, light gray = 2, and white = 3) recovered by the SCSD method.

Image of FIG. 8.
FIG. 8.

Results for different methods in brain DW-MRI, the image shows the intersection of posterior corona radiata and tapetum-splenium of corpus callosum.

Tables

Generic image for table
TABLE I.

Comparison for human brain data, entries show how the solution changes as the number of DEO (#q) is decreased (best values in bold).

Generic image for table
TABLE II.

Performance on experiment for of all the tested methods with b = 3000 and different SNRs (best values in bold). The methods present, as expected, smaller errors for a larger b-value.

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/content/aapm/journal/medphys/38/9/10.1118/1.3626571
2011-08-29
2014-04-24
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Resolving axon fiber crossings at clinical b-values: An evaluation study
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/38/9/10.1118/1.3626571
10.1118/1.3626571
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