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Dosimetric investigation of breath-hold intensity-modulated radiotherapy for pancreatic cancer
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10.1118/1.3668314
/content/aapm/journal/medphys/39/1/10.1118/1.3668314
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/39/1/10.1118/1.3668314

Figures

Image of FIG. 1.
FIG. 1.

Example of an abdominal motion pattern observed by the external respiratory monitoring system during EE–BH. Variations in abdominal motion derived from pulsation of the abdominal aorta and baseline drift were observed.

Image of FIG. 2.
FIG. 2.

Phantom setup. The phantom was made of polystyrene with dimensions of 40 × 40 × 10 cm, and set on a motor-driven base. EDR2 x-ray film was placed at a depth of 4 cm in the phantom, perpendicular to the beam axis. The source–surface distance was 95 cm.

Image of FIG. 3.
FIG. 3.

Boxplots of the ionization chamber measurements. The 95th percentiles of dose deviations between stationary and moving conditions were within ±3%.

Image of FIG. 4.
FIG. 4.

(a) Isodose comparison between stationary (solid) and moving (dashed) conditions, and the γ pass/fail map with the criterion of (b) 2%/1 mm, (c) 3%/3 mm, and (d) 5%/3 mm for the area receiving more than 50% dose for the case with the lowest γ3%/3mm.

Image of FIG. 5.
FIG. 5.

Dose profiles in (left column) lateral direction and (right column) longitudinal direction for the cases with the (a, b) the highest (patient 1, field V) and (c, d) the lowest (patient 7, field V) γ3%/3mm.

Image of FIG. 6.
FIG. 6.

Correlation between BH time and the γ2%/1mm for baseline drift. Negative strong and weak correlations were observed between BH time and the γ2%/1mm for BD0.2mm/s (R = −0.72; p < 0.01) and BD0.4mm/s (R = −0.62; p < 0.01), respectively.

Image of FIG. 7.
FIG. 7.

Histograms of the minimal γ passing rate. Black bar shows the minimal γ3%/3mm and gray the minimal γ5%/3mm. When γ3%/3mm and γ5%/3mm > 90% was considered acceptable, a drift of 5 mm would be the cutoff point.

Tables

Generic image for table
TABLE I.

Treatment information for each field.

Generic image for table
TABLE II.

The γ passing rate for baseline drift.

Generic image for table
TABLE III.

Correlations between BH time and the γD%/dm m for BD0.2mm/ s and BD0.4mm/ s.

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/content/aapm/journal/medphys/39/1/10.1118/1.3668314
2011-12-09
2014-04-21
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Dosimetric investigation of breath-hold intensity-modulated radiotherapy for pancreatic cancer
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/39/1/10.1118/1.3668314
10.1118/1.3668314
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