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Graphical representation of the effects on tumor and OAR for determining the appropriate fractionation regimen in radiation therapy planning
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10.1118/1.4757580
/content/aapm/journal/medphys/39/11/10.1118/1.4757580
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/39/11/10.1118/1.4757580
View: Figures

Figures

Image of FIG. 1.
FIG. 1.

Graphical representation of the relation between surviving fraction for the tumor S 1 and that for the OAR S 0.

Image of FIG. 2.
FIG. 2.

Graphical representation of the relation between effect on the tumor E 1 and that on the OAR E 0 (TO plot).

Image of FIG. 3.
FIG. 3.

The damage effects on the OAR with 2- and 10-fractionated irradiations, derived graphically using the TO plot with Eq. (6).

Image of FIG. 4.
FIG. 4.

When δ is large (e.g., δ = 0.8), conventional fractionated radiotherapy is better because the damage effect on the OAR decreases as the number of irradiations increases. Here, the solid curve is the TO plot.

Image of FIG. 5.
FIG. 5.

When δ is small (e.g., δ = 0.1), hypofractionated radiotherapy is better because the damage effect on the OAR increases as the number of irradiations increases.

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/content/aapm/journal/medphys/39/11/10.1118/1.4757580
2012-10-19
2014-04-24
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Graphical representation of the effects on tumor and OAR for determining the appropriate fractionation regimen in radiation therapy planning
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/39/11/10.1118/1.4757580
10.1118/1.4757580
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