(a) The small animal PET showing its eight modules. (b) Schematic view of PET, showing axial dimensions of the modules active surface (40 mm). The allowed module coincidences reduce geometric aperture from 111 mm to an 80 mm in diameter useful transaxial FOV. In this figure partial cross section of two modules is displayed.
One of the eight modules of the small animal PET (left). Monolithic LYSO crystal. The truncated pyramid shape of the crystal can be appreciated (right).
Schematic view of PET system, showing the planar source used for normalization of the LORs “connecting” modules (1,4), (1,5), (1,6), (5,2), and (5,8). The source is located in the centre of the axial and transaxial FOV. The source is conveniently rotated for normalization of the rest of module pairs.
Absolute axial sensitivity profile obtained using a 30% (358–664 keV, •) and 50% (256–766 keV, Δ) energy windows (EW).
Rtot,j , Rtrue,j , Rscattered,j , Rrandom,j , and RNEC,j as a function of the average activity concentration present at the different acquisitions j for mouse-like phantom.
Same as Fig. 6 for rat-like phantom.
Image quality NEMA phantom used in this work.
Images obtained with the phantom of Fig. 7. For the image reconstruction, a 3D standard MLEM algorithm was used. The final image after 12 iterations is shown. (a) Transverse plane of uniform region; (b) coronal plane; (c) transverse single image slice averaged over the central axial 10-mm length of the rods, used for RC calculation; and (d) water- and air-filled cylindrical inserts.
Mouse images acquired with the PET scanner developed by the authors. On the left, a healthy mouse heart (transaxial, sagittal, and coronal views) and on the right coronal views of a mouse brain during an epileptic episode. The arrows indicate the epileptic focus location.
Spatial resolution values (FWHM in mm) obtained in all three directions at two different axial positions.
RC and SDRC obtained with the image quality NEMA phantom.
Performance parameters of some recent reported small animal PET scanners.
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