(i) Static ventilation images and (ii) ADC maps with color bars indicating ADC in cm2/s are shown for six subjects; subjects (A)–(C) are classified as CLN based on ADC and VDP measurements of the contralateral lung (left lung for subjects A–C), while subjects (D)–(F) are classified as CLC based on elevated ADC and VDP values in the contralateral lung (left lung for subjects D–F).
CT images as shown for (A) a 62-year-old female and (B) a 56-year-old male. (i) Pretreatment and (ii) 3.5 and 1.8 months post-treatment, respectively, with radiological evidence of radiation pneumonitis in the ipsilateral lung. Both subjects were treated with 60 Gy. Radiological RP classifications were (Aii) severe diffuse ground glass opacities and (Bii) moderate diffuse ground glass opacities.
12-month survival curves are shown for CLC subjects and CLN subjects with 12-month survival rates of 2/10 and 3/5, respectively.
Baseline clinical demographics.
Clinical and imaging measurements by contralateral lung classification.
RILI and survival by contralateral lung classification.
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