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4D reconstruction for low-dose cardiac gated SPECT
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10.1118/1.4773868
/content/aapm/journal/medphys/40/2/10.1118/1.4773868
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/40/2/10.1118/1.4773868

Figures

Image of FIG. 1.
FIG. 1.

(a) A transverse slice of the female NCAT phantom; (b) defect location and ROIs for bias-variance analysis and CHO assessment; and (c) ROIs for TAC and uniformity calculations.

Image of FIG. 2.
FIG. 2.

Relative root MSE of the myocardium reconstructed by different methods and dose levels. The results were averaged over 30 noise realizations and the standard deviation values were indicated by the error bars for the different methods.

Image of FIG. 3.
FIG. 3.

Bias-standard deviation plot for the normal (a) and defect (b) ROIs reconstructed by different methods and dose levels. The triangle symbols represent the standard, and the circle and diamond symbols represent half and quarter dose levels, respectively. Note that the smallest reconstruction error (consisting of bias and std) corresponds to the lower-left corner of the plot.

Image of FIG. 4.
FIG. 4.

CHO detection Az results from different methods and dose levels. The results were calculated over 30 normal and 30 defect-present noise realizations and the standard deviation values were indicated by the error bars for the different methods.

Image of FIG. 5.
FIG. 5.

NCAT short-axis slices reconstructed by different methods (Standard: ST121 with 8 M counts; Half: 4 M counts; Quarter: 2 M counts). ED is the slice at end-diastolic time point and ES is the end-systolic. The ideal images are from OSEM reconstruction of the noiseless projection data without degradation of attenuation and scatter.

Image of FIG. 6.
FIG. 6.

Reconstructed short-axis slices from a female patient with mild anterior perfusion defect (Standard: ST121 on 12.8M counts; Half: 6.4M counts; Quarter: 3.2M counts). ED is the slice at end-diastolic time point and ES is the end-systolic. Arrow A: mild ischemia; Arrow B: attenuation artifact.

Image of FIG. 7.
FIG. 7.

Reconstructed short-axis images from a male patient interpreted as normal in terms of wall perfusion and function (Standard: ST121 on 11M counts; Half: 5.5M counts; Quarter: 2.25M counts). ED is the slice at end-diastolic time point and ES is the end-systolic. Arrow: attenuation artifact.

Image of FIG. 8.
FIG. 8.

Normalized cross-sectional intensity profiles of different methods at half dose. For comparison, the profiles of ideal and standard reconstructions are also shown. The insertion shows where the intensity profile was calculated.

Tables

Generic image for table
TABLE I.

Uniformity measure of the LV wall reconstructed by different methods at half and quarter dose levels. Values are averaged over 30 noise realizations with standard deviations in parentheses. The uniformity measure for the standard (ST121 Full) is 9.52 (1.74).

Generic image for table
TABLE II.

CC of TAC of the LV wall reconstructed by different methods at half and quarter dose levels. Values are averaged over 30 noise realizations with standard deviations in parentheses. The value for the standard (ST121 Full) is 0.6647 (0.2010).

Generic image for table
TABLE III.

LVEF of two patients measured by 4D-MSPECT on images reconstructed by different methods at half and quarter dose levels.

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/content/aapm/journal/medphys/40/2/10.1118/1.4773868
2013-01-10
2014-04-20
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: 4D reconstruction for low-dose cardiac gated SPECT
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/40/2/10.1118/1.4773868
10.1118/1.4773868
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