The authors evaluated the absorbed dose received by the gonads during roboticstereotactic radiosurgery(SRS) for the treatment of different tumor localizations.
The authors measured the gonad doses during the treatment of head and neck, thoracic, abdominal, or pelvic tumors in both RANDO phantom and actual patients. The computerized tomography images were transferred to the treatment planning system. The contours of tumor and critical organs were delineated on each slice, and treatment plans were generated. Measurements for gonad doses were taken from the geometric projection of the ovary onto the skin for female patients, and from the scrotal skin for male patients by attaching films and Thermoluminescent dosimeters(TLDs).SRS was delivered with CyberKnife (Accuray Inc., Sunnyvale, CA).
The median gonadal doses with TLD and film dosimeter in actual patients were 0.19 Gy (range, 0.035–2.71 Gy) and 0.34 Gy (range, 0.066–3.18 Gy), respectively. In the RANDO phantom, the median ovarian doses with TLD and film dosimeter were 0.08 Gy (range, 0.03–0.159 Gy) and 0.05 Gy (range, 0.015–0.13 Gy), respectively. In the RANDO phantom, the median testicular doses with TLD and film dosimeter were 0.134 Gy (range 0.056–1.97 Gy) and 0.306 Gy (range, 0.065–2.25 Gy).
Gonad doses are below sterility threshold in roboticSRS for different tumor localizations. However, particular attention should be given to gonads during roboticSRS for pelvic tumors.
Received 06 August 2012Revised 14 February 2013Accepted 16 February 2013Published online 12 March 2013
This study is supported by Hacettepe University Research Grant Project 1-05 A 101 009. The authors report no conflicts of interest in conducting the research.
Article outline: I. INTRODUCTION II. METHODS AND MATERIALS II.A. Calibration of the dosimeters II.B. Measurement of gonadal doses in actual patients II.C. Measurement of gonadal doses in RANDO phantom III. RESULTS III.A. Gonadal doses in actual patients III.B. Gonadal doses in RANDO phantom IV. DISCUSSION V. CONCLUSION
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