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Silicone breast phantoms for elastographic imaging evaluation
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10.1118/1.4805096
/content/aapm/journal/medphys/40/6/10.1118/1.4805096
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/40/6/10.1118/1.4805096

Figures

Image of FIG. 1.
FIG. 1.

Drawings of phantom mold (a) cavity, (b) core, and (c) complete assembly showing 1 mm gap between cavity and core.

Image of FIG. 2.
FIG. 2.

Depth locations of inclusions (a) 5 mm, (b) 10 mm, and (c) 20 mm, and (d) 6-o’ clock position when the breast is viewed from front.

Image of FIG. 3.
FIG. 3.

Molding procedure of silicone breast phantoms: (a) process of core extraction, (b) procedure of placing a stiff tumor into the healthy tissue, (c) cured healthy tissue, (d) circular disc with bolts, (e) method of applying a circular disk during molding of pectoral muscle, (f) the molded breast phantom.

Image of FIG. 4.
FIG. 4.

(a) Mean values, , and (b) Coefficient of variation ( = σ/μ) of storage modulus,

Image of FIG. 5.
FIG. 5.

(a) Mean values, , and (b) coefficient of variation () of damping ratios, .

Image of FIG. 6.
FIG. 6.

Bode plot of healthy (solid) and tumors dataset (dotted) showing shift in the natural frequencies both in terms of magnitude of surface vibration (a) and phase (b).

Image of FIG. 7.
FIG. 7.

Result of -test for phantoms (a) healthy and (b) having a 20 mm tumor at 6-o’ clock. The thresholded outcome 1 − hypothesis rejected (lighter area with value 1) or accepted (dark area with value 0) is shown in each case, indicating an abrupt change in the natural frequencies and thus a stiffer inclusion at the red area.

Image of FIG. 8.
FIG. 8.

MRE reconstruction of a phantom with “composition-B” as background and two inclusions: “composition-C” on the left and “composition-A” on the right. A subset of slices from the full volume data read shown: (a) is a T2* weighted image, (b) is the storage modulus (kPa), (c) is the loss modulus (kPa), and (d) is the damping ratio.

Tables

Generic image for table
TABLE I.

Materials used for mimicking breast tissues and the measured values of Young's modulus by previous investigators.

Generic image for table
TABLE II.

Description of tumor location (depth) in heterogeneous breast phantoms.

Generic image for table
TABLE III.

Materials used for mimicking different tissues in DIET anthropomorphic breast phantoms.

Generic image for table
TABLE IV.

Materials used for mimicking background and inclusions in the MRE phantom.

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/content/aapm/journal/medphys/40/6/10.1118/1.4805096
2013-05-23
2014-04-19
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Silicone breast phantoms for elastographic imaging evaluation
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/40/6/10.1118/1.4805096
10.1118/1.4805096
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