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Lung sparing and dose escalation in a robust-inspired IMRT planning method for lung radiotherapy that accounts for intrafraction motion
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10.1118/1.4805101
/content/aapm/journal/medphys/40/6/10.1118/1.4805101
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/40/6/10.1118/1.4805101

Figures

Image of FIG. 1.
FIG. 1.

The robust-like concept. To enhance organ sparing, beam apertures smaller than those used conventionally are applied. An intensity profile containing horns compensates for the part of the tumor that would escape from such smaller apertures.

Image of FIG. 2.
FIG. 2.

Representative DVH for one patient. Lung sparing and clinical plans were normalized to the dose required to cover 99% of the CTV (D99).

Image of FIG. 3.
FIG. 3.

Dose distribution for lung sparing strategy. Dose distributions are shown on axial and coronal slices for the robust and the clinical plan of one patient. The cPTV is indicated by the largest contour, as shown on both axial and coronal slices. The rPTV contour, which is smaller than the cPTV, is contained within the cPTV contour, as shown on the axial slices. The boost volume is the crescent shaped contour, as shown on the coronal slices.

Image of FIG. 4.
FIG. 4.

CTV coverage reported in terms of D95 and D90. Robust and clinical plans were normalized to D99 of the CTV.

Image of FIG. 5.
FIG. 5.

Representative DVH for one patient. Robust and clinical plans were normalized to non-GTV mean lung dose.

Image of FIG. 6.
FIG. 6.

CTV and rPTV coverage reported in terms of D95 and D90. Robust and clinical plans were normalized to non-GTV mean lung dose.

Image of FIG. 7.
FIG. 7.

Dose distribution for dose escalation strategy. Dose distributions are shown on axial and coronal slices for the robust and the clinical plan. The cPTV is indicated by the largest contour, as shown on both axial and coronal slices. The rPTV contour, which is smaller than the cPTV, is contained within the cPTV contour, as shown on the axial slices. The boost volume is the crescent shaped contour, as shown on the coronal slices.

Tables

Generic image for table
TABLE I.

Tumor characteristics.

Generic image for table
TABLE II.

Percent reduction to (a) non-GTV lung parameters and (b) ipsilateral lung parameters for equal CTV coverage.

Generic image for table
TABLE III.

Percent reduction to (a) non-GTV lung parameters and (b) ipsilateral lung parameters for equal MLD.

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/content/aapm/journal/medphys/40/6/10.1118/1.4805101
2013-05-16
2014-04-20
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Lung sparing and dose escalation in a robust-inspired IMRT planning method for lung radiotherapy that accounts for intrafraction motion
http://aip.metastore.ingenta.com/content/aapm/journal/medphys/40/6/10.1118/1.4805101
10.1118/1.4805101
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