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JADA: A graphical user interface for comprehensive internal dose assessment in nuclear medicine
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Image of FIG. 1.
FIG. 1.

Overview of workflow in the dosimetry program between the 6 subGUIs, which are the main GUI, the GUI, the GUI, the GUI, the GUI, and the GUI.

Image of FIG. 2.
FIG. 2.

Screen capture of the main GUI.

Image of FIG. 3.
FIG. 3.

Screen capture of the GUI. Anterior (left) and posterior (right) views from the first of three planar scans is displayed. The posterior view has been “flipped” from left to right so organs appear in the same locations. A region of interest delineating the spleen and surrounding background is drawn on the posterior view and automatically copied to the anterior. In addition, a background region is drawn to be used for geometric background subtraction.

Image of FIG. 4.
FIG. 4.

Screen capture of the GUI. The top left window displays the reference image, which in this case is a posterior view of the spleen in the first of three whole body planar scans. The bottom left window shows the image of the spleen from the second whole body planar scan registered to the reference image. This registration was performed using the semiautomatic algorithm, which shifted the image to register by one pixel in the vertical direction and rotated it by 3° in the counter clockwise direction. The plots in the top right and bottom right windows are profiles through the reference image and the registered image, which serve to check the accuracy of the registration.

Image of FIG. 5.
FIG. 5.

Screen capture of the GUI demonstrating how reconstructed SPECT images are analyzed. The user draws regions slice by slice in the top left window, with a choice of using a transaxial, coronal, or sagittal view. The remaining two views are displayed in the top right and bottom right windows, which are used to check the slice position. The bottom left window is used for different purposes and in this case it shows outlines of the regions segmented (current region under investigation with a solid line and other segmented regions with a dashed line) from the nuclear medicine image on the corresponding CT slice.

Image of FIG. 6.
FIG. 6.

A subGUI that is called from the GUI for creating DOSXYZnrc/EGSnrc input files.

Image of FIG. 7.
FIG. 7.

Screen capture of the GUI.


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Summary of dosimetry protocol options offered by JADA.

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Example output from organ level absorbed dose calculation.

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Organ dose estimates obtained using the GUI and Monte Carlo simulation and voxel S value dose calculation with the GUI.


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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: JADA: A graphical user interface for comprehensive internal dose assessment in nuclear medicine