Skip to main content

News about Scitation

In December 2016 Scitation will launch with a new design, enhanced navigation and a much improved user experience.

To ensure a smooth transition, from today, we are temporarily stopping new account registration and single article purchases. If you already have an account you can continue to use the site as normal.

For help or more information please visit our FAQs.

banner image
No data available.
Please log in to see this content.
You have no subscription access to this content.
No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.
/content/aip/journal/adva/5/5/10.1063/1.4921317
1.
1.G. M. Whitesides, Nature 442, 368 (2006).
http://dx.doi.org/10.1038/nature05058
2.
2.S. Li, X. Ding, F. Guo, Y. Chen, M. I. Lapsley, S.-C. S. Lin, L. Wang, J. P. McCoy, C. E. Cameron, and T. J. Huang, Anal. Chem. 85, 5468 (2013).
http://dx.doi.org/10.1021/ac400548d
3.
3.F. Guo, P. Li, J. B. French, Z. Mao, H. Zhao, S. Li, N. Nama, J. R. Fick, S. J. Benkovic, and T. J. Huang, Proc. Nati. Acad. Sci. U.S.A. 112, 43 (2015).
http://dx.doi.org/10.1073/pnas.1422068112
4.
4.Y. Yang, A. Q. Liu, L. K. Chin, X. M. Zhang, D. P. Tsai, C. L. Lin, C. Lu, G. P. Wang, and N. I. Zheludev, Nat. Commun. 3, 651 (2012).
http://dx.doi.org/10.1038/ncomms1662
5.
5.Z. Mao, F. Guo, Y. Xie, Y. Zhao, M. I. Lapsley, L. Wang, J. D. Mai, F. Costanzo, and T. J. Huang, J. Lab. Autom. 20, 17 (2014).
http://dx.doi.org/10.1177/2211068214549625
6.
6.J. Wu, W. Cao, W. Wen, D. C. Chang, and P. Sheng, Biomicrofluidics 3, 012005 (2009).
http://dx.doi.org/10.1063/1.3058587
7.
7.X. Yu, R. He, S. Li, B. Cai, L. Zhao, L. Liao, W. Liu, Q. Zeng, H. Wang, S.-S. Guo, and X.-Z. Zhao, Small 9, 3895 (2013).
http://dx.doi.org/10.1002/smll.201300169
8.
8.M. A. Unger, H.-P. Chou, T. Thorsen, A. Scherer, and S. R. Quake, Science 288, 113 (2000).
http://dx.doi.org/10.1126/science.288.5463.113
9.
9.A. Karimi, S. Yazdi, and A. M. Ardekani, Biomicrofluidics 7, 021501 (2013).
http://dx.doi.org/10.1063/1.4799787
10.
10.F. Guo, X.-H. Ji, K. Liu, R.-X. He, L.-B. Zhao, Z.-X. Guo, W. Liu, S.-S. Guo, and X.-Z. Zhao, Appl. Phys. Lett. 96, 193701 (2010).
http://dx.doi.org/10.1063/1.3360812
11.
11.L. Rao, B. Cai, J. Wang, Q. Meng, C. Ma, Z. He, J. Xu, Q. Huang, S. Li, Y. Cen, S. Guo, W. Liu, and X.-Z. Zhao, Sens. Actuators B 210, 328 (2015).
http://dx.doi.org/10.1016/j.snb.2014.12.057
12.
12.Z. Wei, X. Li, D. Zhao, H. Yan, Z. Hu, Z. Liang, and Z. Li, Anal. Chem. 86, 10215 (2014).
http://dx.doi.org/10.1021/ac502294e
13.
13.K.-Y. Lu, A. M. Wo, Y.-J. Lo, K.-C. Chen, C.-M. Lin, and C.-R. Yang, Biosens. Bioelectron. 22, 568 (2006).
http://dx.doi.org/10.1016/j.bios.2006.08.009
14.
14.H. Zhou and S. Yao, Lab Chip 13, 962 (2013).
http://dx.doi.org/10.1039/c2lc41060e
15.
15.Y.-H. Lin, G.-B. Lee, C.-W. Li, G.-R. Huang, and S.-H. Chen, J. Chromatogr. A 937, 115 (2001).
http://dx.doi.org/10.1016/S0021-9673(01)01326-7
16.
16.M. Li, W. H. Li, J. Zhang, G. Alici, and W. Wen, J. Phys. D: Appl. Phys. 47, 063001 (2014).
http://dx.doi.org/10.1088/0022-3727/47/6/063001
17.
17.S. Li, M. Li, Y. Hui, W. Cao, W. Li, and W. Wen, Microfluid. Nanofluid. 14, 499 (2013).
http://dx.doi.org/10.1007/s10404-012-1068-6
18.
18.J. Park, B. Kim, S. K. Choi, S. Hong, S. H. Lee, and K.-I. Lee, Lab Chip 5, 1264 (2005).
http://dx.doi.org/10.1039/b506803g
19.
19.S. Numthuam, T. Kakegawa, T. Anada, A. Khademhosseini, H. Suzuki, and J. Fukuda, Sens. Actuators B 156, 637 (2011).
http://dx.doi.org/10.1016/j.snb.2011.02.010
20.
20.N. Lewpiriyawong and C. Yang, Biomicrofluidics 6, 012807 (2012).
http://dx.doi.org/10.1063/1.3682049
21.
21.D. Chen and H. Du, Microfluid. Nanofluid. 3, 603 (2007).
http://dx.doi.org/10.1007/s10404-007-0151-x
22.
22.X. Z. Niu, S. L. Peng, L. Y. Liu, W. J. Wen, and P. Sheng, Adv. Mater. 19, 2682 (2007).
http://dx.doi.org/10.1002/adma.200602515
23.
23.N. Lewpiriyawong, K. Kandaswamy, C. Yang, V. Ivanov, and R. Stocker, Anal. Chem. 83, 9579 (2011).
http://dx.doi.org/10.1021/ac202137y
24.
24.J. Voldman, M. Toner, M. L. Gray, and M. A. Schmidt, J. Electrostatics 57, 69 (2003).
http://dx.doi.org/10.1016/S0304-3886(02)00120-1
25.
25.C. Iliescu, L. Yu, F. E. H. Tay, and B. Chen, Sens. Actuators B 129, 491 (2008).
http://dx.doi.org/10.1016/j.snb.2007.11.023
26.
26.J.-W. Choi, S. Rosset, M. Niklaus, J. R. Adleman, H. Shea, and D. Psaltis, Lab Chip 10, 783 (2010).
http://dx.doi.org/10.1039/b917719a
27.
27.A. C. Siegel, S. S. Shevkoplyas, D. B. Weibel, D. A. Bruzewicz, A. W. Martinez, and G. M. Whitesides, Angew. Chem. 118, 7031 (2006).
http://dx.doi.org/10.1002/ange.200602273
28.
28.A. C. Siegel, D. A. Bruzewicz, D. B. Weibel, and G. M. Whitesides, Adv. Mater. 19, 727 (2007).
http://dx.doi.org/10.1002/adma.200601787
29.
29.J.-C. Baret, O. J. Miller, V. Taly, M. Ryckelynck, A. El-Harrak, L. Frenz, C. Rick, M. L. Samuels, J. B. Hutchison, J. J. Agresti, D. R. Link, D. A. Weitz, and A. D. Griffiths, Lab Chip 9, 1850 (2009).
http://dx.doi.org/10.1039/b902504a
30.
30.N. Hallfors, A. Khan, M. D. Dickey, and A. M. Taylor, Lab Chip 13, 522 (2013).
http://dx.doi.org/10.1039/C2LC40954B
31.
31.Y. Xia and G. M. Whitesides, Angew. Chem. Int. Ed. 37, 550 (1998).
http://dx.doi.org/10.1002/(SICI)1521-3773(19980316)37:5%3C550::AID-ANIE550%3E3.0.CO;2-G
32.
32.X. Liu, X. Liu, J. Wang, C. Liao, X. Xiao, S. Guo, C. Jiang, Z. Fan, T. Wang, X. Chen, W. Lu, W. Hu, and L. Liao, Adv. Mater. 26, 7399 (2014).
http://dx.doi.org/10.1002/adma.201401732
33.
33.K. Liu, Y. Deng, N. Zhang, S. Li, H. Ding, F. Guo, W. Liu, S. Guo, and X.-Z. Zhao, Microfluid. Nanofluid. 13, 761 (2012).
http://dx.doi.org/10.1007/s10404-012-0998-3
34.
34.M. Z. Bazant and T. M. Squires, Phys. Rev. Lett. 92, 066101 (2004).
http://dx.doi.org/10.1103/PhysRevLett.92.066101
35.
35.M. E. Leunissen, A. van Blaaderen, A. D. Hollingsworth, M. T. Sullivan, and P. M. Chaikin, Proc. Nati. Acad. Sci. U.S.A. 104, 2585 (2007).
http://dx.doi.org/10.1073/pnas.0610589104
36.
36.W. D. Ristenpart, J. C. Bird, A. Belmonte, F. Dollar, and H. A. Stone, Nature 461, 377 (2009).
http://dx.doi.org/10.1038/nature08294
37.
37.B. Cai, F. Guo, L. Zhao, R. He, B. Chen, Z. He, X. Yu, S. Guo, B. Xiong, W. Liu, and X.-Z Zhao, Microfluid. Nanofluid. 6, 29 (2014).
http://dx.doi.org/10.1007/s10404-013-1198-5
38.
38.Q. Huang, B. Chen, R. He, Z. He, B. Cai, J. Xu, W. Qian, H. L. Chan, W. Liu, S. Guo, X.-Z. Zhao, and J. Yuan, Adv. Healthcare Mater. 3, 1420 (2014).
http://dx.doi.org/10.1002/adhm.201300670
39.
39.D. R. Link, E. Grasland-Mongrain, A. Duri, F. Sarrazin, Z. Cheng, G. Cristobal, M. Marquez, and D. A. Weitz, Angew. Chem. Int. Ed. 45, 2556 (2006).
http://dx.doi.org/10.1002/anie.200503540
40.
40.F. Guo, M. I. Lapsley, A. A. Nawaz, Y. Zhao, S.-C. S. Lin, Y. Chen, S. Yang, X.-Z. Zhao, and T. J. Huang, Anal. Chem. 84, 10745 (2012).
http://dx.doi.org/10.1021/ac302623z
http://aip.metastore.ingenta.com/content/aip/journal/adva/5/5/10.1063/1.4921317
Loading
/content/aip/journal/adva/5/5/10.1063/1.4921317
Loading

Data & Media loading...

Loading

Article metrics loading...

/content/aip/journal/adva/5/5/10.1063/1.4921317
2015-05-14
2016-12-08

Abstract

3D microelectrodes are one-step fabricated into a microfluidic droplet separator by filling conductive silver paste into PDMS microchambers. The advantages of 3D silver paste electrodes in promoting droplet sorting accuracy are systematically demonstrated by theoretical calculation, numerical simulation and experimental validation. The employment of 3D electrodes also helps to decrease the droplet sorting voltage, guaranteeing that cells encapsulated in droplets undergo chip-based sorting processes are at better metabolic status for further potential cellular assays. At last, target droplet containing single cell are selectively sorted out from others by an appropriate electric pulse. This method provides a simple and inexpensive alternative to fabricate 3D electrodes, and it is expected our 3D electrode-integrated microfluidic droplet separator platform can be widely used in single cell operation and analysis.

Loading

Full text loading...

/deliver/fulltext/aip/journal/adva/5/5/1.4921317.html;jsessionid=1imqocWYlnRHOFJHZQypamwd.x-aip-live-03?itemId=/content/aip/journal/adva/5/5/10.1063/1.4921317&mimeType=html&fmt=ahah&containerItemId=content/aip/journal/adva
true
true

Access Key

  • FFree Content
  • OAOpen Access Content
  • SSubscribed Content
  • TFree Trial Content
752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
/content/realmedia?fmt=ahah&adPositionList=
&advertTargetUrl=//oascentral.aip.org/RealMedia/ads/&sitePageValue=aipadvances.aip.org/5/5/10.1063/1.4921317&pageURL=http://scitation.aip.org/content/aip/journal/adva/5/5/10.1063/1.4921317'
Right1,Right2,Right3,