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Direct visualization of the transdermal transport of fluorescent nanoparticles (490 NCs) and sulforhodamine B in human skin specimen (a) without and (b) with oleic acid treatment. (Red: sulforhodaine B, blue: 490 NC).
Magnified multiphoton images of skin treated with oleic acid. Fluorescence channels for 490 NCs (a) and SRB (b) molecules are displayed separately. Intensity profiles of 490 NCs and SRB across the marked line are also shown.
Depth-dependent intensity profiles of (a) 490 NCs and (b) SRB (with and without oleic acid treatment).
Statistics of transdermal transport properties of SRB and NC within oleic acid-treated and untreated porcine samples ex vivo (OA: oleic acid).
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