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Taking whispering gallery-mode single virus detection and sizing to the limit
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/content/aip/journal/apl/101/4/10.1063/1.4739473
2012-07-27
2014-10-22

Abstract

We report the label-free detection and sizing by a microcavity of the smallest individual RNAvirus, MS2, with a mass only ∼1% of InfluenzaA (6 vs. 512 ag). Although detection of such a small bio-nano-particle has been beyond the reach of a bare spherical microcavity, it was accomplished with ease (S/N = 8, Q = 4 × 105) using a single dipole stimulated plasmonic-nanoshell as a microcavity wavelength shift enhancer, providing an enhancement of ∼70×, in agreement with theory. Unique wavelength shift statistics are recorded consistent with an ultra-uniform genetically programmed substance that is drawn to the plasmonic hot spots by light-forces.

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Scitation: Taking whispering gallery-mode single virus detection and sizing to the limit
http://aip.metastore.ingenta.com/content/aip/journal/apl/101/4/10.1063/1.4739473
10.1063/1.4739473
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