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Digital optical phase conjugation of fluorescence in turbid tissue
6. Photodynamic Therapy, Comprehensive Series in Photochemical & Photobiological Sciences, edited by T. Patrice (RSC, London, 2003).
11. Optical Phase Conjugation, edited by R. A. Fisher (Academic, New York, 1983).
13. The theoretical maximum intensity of binary phase modulation is a factor 4/π2 lower than with full phase modulation (also see Ref. 22).
14. J. W. Goodman, Statistical Optics (Wiley, New York, 2000).
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We demonstrate a method for phase conjugating fluorescence. Our method, called reference free digital optical phase conjugation, can conjugate extremely weak, incoherent optical signals. It was used to phase conjugate fluorescent light originating from a bead covered with 0.5 mm of light-scattering tissue. The phase conjugated beam refocuses onto the bead and causes a local increase of over two orders of magnitude in the light intensity. Potential applications are in imaging, optical trapping, and targeted photochemical activation inside turbid tissue.
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