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Observation of terahertz absorption signatures in microliter DNA solutions
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View: Figures


Image of FIG. 1.
FIG. 1.

Conical-horn coupler at the middle of the THz path of THz coherent transceiver. Two laser beams, one from fixed DFB laser (λ = 780 nm) and the other from the tunable DFB laser (>780 nm) are combined at beam combiner.

Image of FIG. 2.
FIG. 2.

(a) The spectra of background, sample, and noise floor. (b) The transmission calculated from (a).

Image of FIG. 3.
FIG. 3.

(a) The relative transmission measured at different times under exactly the same conditions. The top (green) curve was measured approximately 2.5 h after the bottom (black) curve. (b) Transmitted signal through the 590-μm-diam hole in a 130-μm-thick shim filled with buffer-solution (no DNA) only.

Image of FIG. 4.
FIG. 4.

The fitting of attenuation coefficient around the 720 GHz resonance using the Lorentz oscillator equation.

Image of FIG. 5.
FIG. 5.

An elastic model to illustrate the local cross-linking of two separate ssDNA molecules in solution. m1 represents PO4 groups, m2 represents the sugar rings, and m3 represents the bases. The detailed discussion of DNA lattice model can be found in Ref. 6 . f11, f12, f23, f33 are elastic force constants. Two ssDNA chains are assumed to be connected together through a single hydrogen bond. The 720 GHz resonance occurs when the individual oscillator with fH is excited.


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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Observation of terahertz absorption signatures in microliter DNA solutions