Index of content:
Volume 104, Issue 13, 31 March 2014
We introduce an approach and describe the process of acoustically driven formation of droplets in a microfluidic T-junction. Our system allows for fast and precise control of drop volume over a wide range that is fully electrically triggered. We exploit the interaction of a surface acoustic wave (SAW) excited on a piezoelectric, transparent substrate with the fluid to adjust the size of drops in a continuous microflow in real time and relate SAW intensity and drop size. Our device operates in the squeezing regime at low capillary numbers. We describe the mechanism of SAW modulated formation of a monodisperse microemulsion that forms the basis for the integration of more complex operations useful for droplet fluidic systems.
- BIOPHYSICS AND BIO-INSPIRED SYSTEMS
104(2014); http://dx.doi.org/10.1063/1.4870623View Description Hide Description
Atmospheric pressure plasma (APP) has been recognized as a promising tool for cancer therapy based on its ability to remove cancer cells by causing apoptosis and necrosis. However, the effect of APP on the neighboring tissues of tumors remains unknown. Moreover, the role of APP on the vessels near tumors could be very important, because once a tumor becomes vascularized, the potential for metastasis can increase dramatically. We show in the present study that APP can induce cell cycle arrest in endothelial cells and further suppress the angiogenesis process. These results strongly support the use of APP in cancer treatment.