No data available.
Please log in to see this content.
You have no subscription access to this content.
No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.
Intrinsic defect formation in peptide self-assembly
4. C. Kittel, Introduction to Solid State Physics ( John Wiley & Sons, New York, 2005).
12. M. R. Sawaya, S. Sambashivan, R. Nelson, M. I. Ivanova, S. A. Sievers, M. I. Apostol, M. J. Thompson, M. Balbirnie, J. J. W. Wiltzius, H. T. McFarlane, A. O. Madsen, C. Riekel, and D. Eisenberg, Nature 447(7143), 453 (2007).
13. A. W. P. Fitzpatrick, G. T. Debelouchina, M. J. Bayro, D. K. Clare, M. A. Caporini, V. S. Bajaj, C. P. Jaroniec, L. C. Wang, V. Ladizhansky, S. A. Muller, C. E. MacPhee, C. A. Waudby, H. R. Mott, A. De Simone, T. P. J. Knowles, H. R. Saibil, M. Vendruscolo, E. V. Orlova, R. G. Griffin, and C. M. Dobson, Proc. Natl. Acad. Sci. U.S.A. 110(14), 5468 (2013).
24. A. Aggeli, I. A. Nyrkova, M. Bell, R. Harding, L. Carrick, T. C. B. McLeish, A. N. Semenov, and N. Boden, Proc. Natl. Acad. Sci. U.S.A. 98(21), 11857 (2001).
29. D. Frenkel and B. Smit, Understanding Molecular Simulation: From Algorithms to Applications ( Academic Press, New York, 2001).
31. C. Lin and M. J. Perry, Proceedings of IEEE Workshop on Computer Vision: Representation and Control ( IEEE Computer Society Press, Silver Spring, 1982).
Article metrics loading...
In contrast to extensively studied defects in traditional materials, we report here a systematic investigation of the formation mechanism of intrinsic defects in self-assembled
peptide nanostructures. The Monte Carlo simulations with our simplified dynamic hierarchical model revealed that the symmetry breaking of layer bending mode at the two ends during morphological transformation is responsible for intrinsic defect formation, whose microscopic origin is the mismatch between layer stacking along the side-chain direction and layer growth along the hydrogen bond direction. Moreover, defect formation does not affect the chirality of the self-assembled structure, which is determined by the initial steps of the peptide
Full text loading...
Most read this month