banner image
No data available.
Please log in to see this content.
You have no subscription access to this content.
No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
Adaptive optical biocompact disk for molecular recognition
Rent this article for
View: Figures


Image of FIG. 1.
FIG. 1.

The AO-BioCD disk and probe geometry that converts a periodic pattern of printed protein on a spinning disk into a high-frequency phase modulation. The figure shows the adaptive BioCD layout (bottom), the probing scheme (top-right), and fluorescence photo of the protein pattern (top-left).

Image of FIG. 2.
FIG. 2.

The AO-BioCD calibration. (a) The homodyne signal spectrum of printed BSA. Insert: the atomic force microscope scan of the edge of one BSA spoke. (b) The homodyne signal spectrum of the phase modulator, driven by a 5 MHz ac voltage with , which generates a phase modulation of for an equivalent optical thickness of 2.8 nm.

Image of FIG. 3.
FIG. 3.

The AO-BioCD Immunoassay results. (a) Single-analyte experiment detecting specific binding between mouse IgG and anti-mouse IgG. Tracks B and C are incubated with specific antibody, showing positive detection. (b) Two-analyte experiment detecting specific bindings between mouse IgG (rabbit IgG) and anti-mouse IgG (anti-rabbit IgG). Tracks B and C were incubated with rabbit, and C and D were incubated with mouse antibody. The overlapping detection in Track C cancels out.


Article metrics loading...


Full text loading...

This is a required field
Please enter a valid email address
752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Adaptive optical biocompact disk for molecular recognition