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Field-effect control of protein transport in a nanofluidic transistor circuit
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View: Figures


Image of FIG. 1.
FIG. 1.

Nanofluidic transistor. (a) Schematic of a nanofluidic transistor. The gate voltage can be used to control the ionic concentration in the nanochannel via field effect. (b) Schematic of the transistor-reservoir-transistor system connected with microfluidic channels on either side. (c) Micrograph of the fabricated device, with long channels (scale bar is ).

Image of FIG. 2.
FIG. 2.

Effect of gate voltage without bias between the microchannels. (a) Schematic showing diffusion of avidin when the transistor is turned on without bias between the microchannels. (b) Fluorescence images corresponding to (a). (c) Line plots of fluorescence intensities (background subtracted) along a representative channel showing diffusion of avidin along the channel. Numbers on the line plots denote time in minutes.

Image of FIG. 3.
FIG. 3.

Effect of gate voltage with bias applied between the microchannels. (a) Variation of fluorescence intensity in the central reservoirs (measured along the dotted line, inset) with time as the transistor is switched on and off. Gate voltage is switched from (on) to (off) at (1), to (on) at (2) and to (off) at (3). (b) Line plots of fluorescence intensity (background subtracted) in the central reservoirs (along dotted line, inset) show the transistor in the on and off states corresponding to the sequence in (a).


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Scitation: Field-effect control of protein transport in a nanofluidic transistor circuit