Spatio-temporally-complex concentration profiles using a tunable chaotic micromixer
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(Color online) Operation of the . (a) Flow in the microchannel is not stirred when the PDMS membranes are not pressurized; flow is from left to right. (b) Flow is stirred when suction is applied to the pneumatic line, deflecting the membrane downwards (deflection depending on ), which forms grooves. (c) Schematic diagram of the (with stripes at 45° angle, wide, deep and separation). (d)–(f) Optical micrographs illustrating temporal sequences of concentration gradients of yellow dye, water, and blue dye generated by the (the microchannel is wide and tall; the outlet channels are wide and tall) when (d), (e), and (f) is applied to the pneumatic channel; flow is from top to bottom. Scale bar=.
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(Color online) Parallel generation of multiple time-variable concentrations of fluorescein with the . (a)–(c) Fluorescence micrographs of the device for (a), (b), and (c); flow is from top to bottom. Scale bar=. (d) Plots of relative concentration of fluorescein as a function of channel number (gradients) for the range ; the three gradients in (a) are highlighted with an arrow; the vertical shading has been added to emphasize differences in relative concentration. (e) Fluorescence intensity values in each of the ten outlet channels vs (or time); the values are normalized to the value.
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