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Electrical detection of hybridization and threading intercalation of deoxyribonucleic acid using carbon nanotube network field-effect transistors
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10.1063/1.2399355
/content/aip/journal/apl/89/23/10.1063/1.2399355
http://aip.metastore.ingenta.com/content/aip/journal/apl/89/23/10.1063/1.2399355
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Figures

Image of FIG. 1.
FIG. 1.

(a) Schematic illustration of the network devices and a typical atomic force microscope image showing strands of SWNT and catalyst particles in the active channel area. (b) Sequences of the synthetic oligonucleotide, , and their complementary and single-base mismatched target analytes. (c) Structure of PIND and PIND-Os intercalators.

Image of FIG. 2.
FIG. 2.

Typical gate voltage dependence of the normalized drain current (normalized by the initial drain current of their bare device at ) for (a) a CNNFET bare device immobilized with , hybridized with complementary target analyte, (b) a CNNFET bare device, immobilized with , hybridized with single-base mismatched target analyte, and immersed with the PIND-Os intercalator (source-drain bias was kept at ).

Image of FIG. 3.
FIG. 3.

(a) Statistical comparisons of sequential reduction in for CNNFETs (left column: eight devices in total with channel lengths of 5, 10, 50, 75, and ; right column: six devices in total with channel lengths of 5, 25, and ) after immobilization, hybridization (complementary: hybridized with complementary DNA; mismatched: hybridized with single base mismatched DNA), and intercalation. (b) XPS comparison of the Os contents for two selected CNNFETs after PIND-Os intercalation.

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/content/aip/journal/apl/89/23/10.1063/1.2399355
2006-12-04
2014-04-17
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Electrical detection of hybridization and threading intercalation of deoxyribonucleic acid using carbon nanotube network field-effect transistors
http://aip.metastore.ingenta.com/content/aip/journal/apl/89/23/10.1063/1.2399355
10.1063/1.2399355
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