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Light-addressable electrode with hydrogenated amorphous silicon and low-conductive passivation layer for stimulation of cultured neurons
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10.1063/1.2709627
/content/aip/journal/apl/90/9/10.1063/1.2709627
http://aip.metastore.ingenta.com/content/aip/journal/apl/90/9/10.1063/1.2709627
View: Figures

Figures

Image of FIG. 1.
FIG. 1.

Schematic diagram of the proposed electrode. Illumination to the electrode increases the conductivity of layer and addresses a stimulating site.

Image of FIG. 2.
FIG. 2.

Temporal change of the electrode luminous sensitivities during exposure to culture medium. The epoxy binder and an acrylic binder were tested. Luminous sensitivity is defined as the dark-to-bright impedance ratio at .

Image of FIG. 3.
FIG. 3.

Photoelectric property of the electrode. Charge densities generated by voltage-controlled pulse application (top panel) and the bright-to-dark ratios (bottom panel) are plotted against voltages applied. Power densities of illumination provided to the electrode were varied from . Error bars are the standard deviation (SD) from four electrodes.

Image of FIG. 4.
FIG. 4.

(Color) Neuronal activation induced by light-addressed stimulation. Difference ratios between pre- and poststimulus fluorescence intensities, , are color-coded above SD and imposed on the raw fluorescence images. Each fluorescence image was recorded with the exposure time of . The broken line shows a locally illuminated area.

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/content/aip/journal/apl/90/9/10.1063/1.2709627
2007-02-26
2014-04-20
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Light-addressable electrode with hydrogenated amorphous silicon and low-conductive passivation layer for stimulation of cultured neurons
http://aip.metastore.ingenta.com/content/aip/journal/apl/90/9/10.1063/1.2709627
10.1063/1.2709627
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