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Nanopore in metal-dielectric sandwich for DNA position control
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View: Figures


Image of FIG. 1.
FIG. 1.

A schematic of the DNA transistor. The shaded regions in the sketch are conducting, while the nonshaded are insulating. The negative charges of the ssDNA are represented by the solid circles: (a) cross section and (b) top view.

Image of FIG. 2.
FIG. 2.

Trapping potential of the ssDNA: (a) when the sidewall length is a half integer (in units of the intercharge distance ), and the potential well thickness is slightly larger than integer length, there are displacements for which the force of the charges (gray arrows) produces a net force on the polymer, as shown in (b), with displacements for which there is a rightward force, no force, and a leftward force. (c) The poterntial of the force depicted in (b) and the effective trapping barrier . The optimal (maximal) trapping barrier is obtained in the case in which is integer and is half integer.

Image of FIG. 3.
FIG. 3.

Time evolution of DNA position distribution during one cycle of digital electrophoresis: The black solid lines correspond to the distribution of positions for a reference nucleotide in the polynucleotide within the nanopore at the latest time indicated in the different subfigures. The black dotted lines indicate the distribution of the reference nucleotide at previous times. The gray lines represent the trapping potential (a) equilibrium: trapping potential is applied (b) drag and diffusion: the trapping potential is removed (indicated by gray line drawn as dotted); (c) retrapping: trapping potential is reapplied.


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Scitation: Nanopore in metal-dielectric sandwich for DNA position control