1887
banner image
No data available.
Please log in to see this content.
You have no subscription access to this content.
No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
Real-time label-free quantitative monitoring of biomolecules without surface binding by floating-gate complementary metal-oxide semiconductor sensor array integrated with readout circuitry
Rent:
Rent this article for
USD
10.1063/1.2803848
/content/aip/journal/apl/91/20/10.1063/1.2803848
http://aip.metastore.ingenta.com/content/aip/journal/apl/91/20/10.1063/1.2803848
View: Figures

Figures

Image of FIG. 1.
FIG. 1.

(Color online) (a) Schematics of a floating-gate field-effect transistor sensing device and label-free detection. The surface potential change is determined by the amount of DNA molecules in the Debye length of the solution. (b) Microphotographs of the fabricated sensor chip and the magnified view of the sensing element.

Image of FIG. 2.
FIG. 2.

Surface potential change between the sample and reference chamber as a function of time for the sequential injection of various oligonucleotides solutions (1, 2, 5, and , respectively). A phosphate buffer solution is introduced before and after injecting oligonucleotides solutions for regenerating the sensing surface.

Image of FIG. 3.
FIG. 3.

(Color online) Surface potential for various oligonucleotides concentrations. Solid and dotted lines show the measurement results and the theoretical calculations as a function of various oligonucleotides concentrations for the two different buffer solutions of 6 and 7, respectively. The error bar represents the standard deviation from the measured responses from 16 elements in the sensor array.

Loading

Article metrics loading...

/content/aip/journal/apl/91/20/10.1063/1.2803848
2007-11-13
2014-04-16
Loading

Full text loading...

This is a required field
Please enter a valid email address
752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Real-time label-free quantitative monitoring of biomolecules without surface binding by floating-gate complementary metal-oxide semiconductor sensor array integrated with readout circuitry
http://aip.metastore.ingenta.com/content/aip/journal/apl/91/20/10.1063/1.2803848
10.1063/1.2803848
SEARCH_EXPAND_ITEM