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Schematic of the LEAC sensor.
Light intensity along the waveguide. The adlayer (shown in the inset) is present in the region between the two dashed lines.
(a) Topography of a -thick immunoassay complex without CRP. (b) Light intensities along the waveguide for clean areas (filled circles) and topographic high points that are not included in the fit (open circles). (c) Measured light intensity modulation and BPM simulation results with different adlayer thickness on -tall ridge. (d) Light intensity modulation vs ridge height for approximately -thick adlayers according to 2D BPM simulations (stars and dashed line) and measured data (open circles).
CRP concentration/adlayer thickness vs intensity.
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