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Separation enhancement in pinched flow fractionation
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View: Figures


Image of FIG. 1.
FIG. 1.

The principle of (a) PFF and (b) EPFF. Suspended particles are aligned (pinched) against a wall in the pinch segment and separated as they move into the broadening segment due to expansion of the laminar flow sheet. In EPFF the separation is amplified by expanding the part of flow sheet that contains particles. The inset illustrates the so-called corner effect.

Image of FIG. 2.
FIG. 2.

Separation of polystyrene microspheres with radii of 0.5 and in (a) a PFF device and (b) an EPFF device. Each bead size is displaced further from the wall and the separation is amplified in EPFF with regard to the PFF device.

Image of FIG. 3.
FIG. 3.

(a) Distance between the bead position in the broadening segment and the channel wall and in the PFF and EPFF device, respectively, as a function of the particle radius. Each measurement data point represents beads, and the error bars represents the standard deviation of the measurements. (b) The SEF as a function of the particle radius.


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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Separation enhancement in pinched flow fractionation