1887
banner image
No data available.
Please log in to see this content.
You have no subscription access to this content.
No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
Highly uniform, strongly correlated fluorinated lipid nanodomains embedded in biological membrane models
Rent:
Rent this article for
USD
10.1063/1.3028088
/content/aip/journal/apl/93/21/10.1063/1.3028088
http://aip.metastore.ingenta.com/content/aip/journal/apl/93/21/10.1063/1.3028088
View: Figures

Figures

Image of FIG. 1.
FIG. 1.

(a) Schematic illustration of a supported lipid monolayer displaying domains of FL17. Molecular structure of FL17 (space filling model) is presented as an inset. (b) Fluorescence image of a supported phospholipid monolayer with FL17 and TR-DHPE. The region of interest (, indicated by the red/dark square) is sampled from each image, and images are subjected to the image analysis. The domains of FL17 (highlighted in dark/red) are identified from the surrounding phospholipids matrix (blue/background) by the contrast in the pixel values. The zoom-up image (inset) suggests the formation of submicrometer domains. (c) 2D Fourier transformation of images would reveal a broad halo around the center. Radial integration of the circular halo (inset) the characteristic lengths .

Image of FIG. 2.
FIG. 2.

(a) Schematic view of the analyzer crystal setup used for GID measurements. (b) The intensity of the diffracted beam from the monolayer with FL17, integrated along . The complete reciprocal space map is available online [supplemental Information (Ref. 7)]. The characteristic distance between fluorocarbon chains and the size of crystallites can be calculated, respectively.

Image of FIG. 3.
FIG. 3.

Distribution function of the distance to the nearest neighbor plotted vs . The black line represents a Gaussian fit for each molar fraction. Though the decrease in FL17 leads to an increase in the peak position and width, a distinct peak can be observed even at .

Image of FIG. 4.
FIG. 4.

(a) The radial distribution function of microdomains vs . Note that a broad peak observed in Fig. 3 cannot be identified, as takes all correlations into account. (b) The potential of mean force vs calculated from the inverse work theorem . More than one order can be observed at , indicating a strong correlation between self-assembled FL17 domains, ranging up to . Spring constants derived from a harmonic potential fit of the first order minima systematically increase with FL17.

Loading

Article metrics loading...

/content/aip/journal/apl/93/21/10.1063/1.3028088
2008-11-25
2014-04-17
Loading

Full text loading...

This is a required field
Please enter a valid email address
752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Highly uniform, strongly correlated fluorinated lipid nanodomains embedded in biological membrane models
http://aip.metastore.ingenta.com/content/aip/journal/apl/93/21/10.1063/1.3028088
10.1063/1.3028088
SEARCH_EXPAND_ITEM