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Efficient microfluidic particle separation arrays
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View: Figures


Image of FIG. 1.
FIG. 1.

Illustration showing the separation method. The periodic flow patterns, or streamlines, are highlighted in blue, green, and yellow; a small particle, green, is able to follow the fluid flow, while the large particle, red, is excluded from the leftmost streamline in each gap. This causes the large particle to move at an angle to the flow fluid and makes separation possible.

Image of FIG. 2.
FIG. 2.

Image collage showing beads that are significantly above the critical particle size in an array with (a) uncorrected and (b) corrected edges. The array in (a) has gaps, posts, and a slope of 1/20, giving a nominal critical size of . The beads are in diameter, 56% above the critical size. In (b) the posts are , the gap is , with , giving a critical particle size of . The beads are in diameter, 45% above the critical size.

Image of FIG. 3.
FIG. 3.

Fluid simulations showing models with (a) uncorrected and (b) corrected edges. A closer look at the (c) left and (d) right edges showing a few stall lines.

Image of FIG. 4.
FIG. 4.

(a) Plot of simulated critical size vs horizontal position for randomly selected positions within the arrays. (b) The poor uniformity in the uncorrected array destroys the characteristic bimodal separation of DLD arrays.


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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Efficient microfluidic particle separation arrays