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Ordered Si nanoaperture arrays for the measurement of ion currents across lipid membranes
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View: Figures


Image of FIG. 1.
FIG. 1.

Formation of a small array of ordered channels in Si. The optical microscopy images show (a) the well etched into the backside of the Si sample and (b) the area on the front side of the sample after MIS. The dashed square outlines the bottom of the well opposite to the seeded front side. (c) shows the optical transmission through the array of anodically etched channels after the second KOH etching step and (d) is a schematic representation of the sample cross section.

Image of FIG. 2.
FIG. 2.

Reduction in channel aperture by thin film deposition: (a) scanning electron microscopy image of an as-prepared macroporous array, (b) the same array after PECVD deposition of a thin film over the array for 40 min, (c) after PECVD deposition for 70 min, and (d) cross section of the array from (b).

Image of FIG. 3.
FIG. 3.

Fluorescence microscopy images of a lipid membrane formed by vesicle fusion over the nanoaperture array from Fig. 2(c). The figures [(a)–(c)] show the effect of a continuous luminescence excitation. After an enlargement of the observation spot in (c) the sample has been kept in darkness before the next fluorescence recording shown in (d), demonstrating the fluidity of the membrane formed on top of the nanoaperture array.


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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Ordered Si nanoaperture arrays for the measurement of ion currents across lipid membranes