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Combining x-ray and photoacoustics for in vivo tumor imaging with gold nanorods
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10.1063/1.3643033
/content/aip/journal/apl/99/12/10.1063/1.3643033
http://aip.metastore.ingenta.com/content/aip/journal/apl/99/12/10.1063/1.3643033
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Figures

Image of FIG. 1.
FIG. 1.

(Color online) (a) Normalized absorption spectra of PEG-GNRs, blood, and blood plus PEG-GNRs. Inset: a typical TEM image of the PEG-GNRs. (b) PA signal intensity of the tumor region after PEG-GNRs injection in vivo. Results are a summary of three independent experiments.

Image of FIG. 2.
FIG. 2.

(Color online) X-ray images of a mouse before injection (a), 5 min (b), 90 min (c), and 300 min (d) after injection of PEG-GNRs. (e) Time-dependent average x-ray signal intensity ratio between tumor region and normal tissue region (T/N ratio).

Image of FIG. 3.
FIG. 3.

(Color online) Noninvasive PA imaging of a tumor in vivo employing PEG-GNRs. PA image acquired before injection (a), 5 min (b), and 90 (c) min after injection of PEG-GNRs. (d) Differential image obtained by subtracting the preinjection image (Fig. 3(a)) from the post-injection image (Fig. 3(b)). (e) Reconstruction profile of image (a) (black line) and image (b) (red dash line) at the position indicated by dashed lines.

Image of FIG. 4.
FIG. 4.

(Color online) Combined x-ray and PA images of a mouse tumor in vivo. (a) Overlay of x-ray image and PA image. (b) Enlargement of corresponding image area highlighted by a square in panel (a).

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/content/aip/journal/apl/99/12/10.1063/1.3643033
2011-09-21
2014-04-17
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Combining x-ray and photoacoustics for in vivo tumor imaging with gold nanorods
http://aip.metastore.ingenta.com/content/aip/journal/apl/99/12/10.1063/1.3643033
10.1063/1.3643033
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