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A symmetric metamaterial element-based RF biosensor for rapid and label-free detection
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View: Figures


Image of FIG. 1.
FIG. 1.

(Color online) Schematic view of the designed biosensing device. The dimensions of the designed element (or resonator) are s = 0.2 mm, w =0.2 mm, g = 0.1 mm, lx = ly = 1.8 mm, respectively. In the case of the high impedance microstrip line, the width and length of a narrow line having a high-impedance characteristic (∼80 Ω) are 0.2 mm and 3.0 mm, respectively. Also, the line is tapered from 0.78 mm to 0.2 mm.

Image of FIG. 2.
FIG. 2.

(Color online) S 21-resonance of a sample and biological process: (a) the measured result with a masking layer (thick red line) and the simulated result without masking (thin black line) are shown. A local surface of the fabricated sample is magnified by an optical microscope. (b) Schematic representation for the detection of PSA.

Image of FIG. 3.
FIG. 3.

(Color online) Frequency behavior of the Cy3-protein G coupled with PSA antibody, and the PSA binding with three different concentrations, and the PSA antibody control: the PSA concentration of (a) 100 ng/ml, (b) 10 ng/ml, and (c) 1 ng/ml; (d) the PSA antibody concentration of 500 ng/ml. (e) The overall frequency behavior for biomolecular binding.


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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: A symmetric metamaterial element-based RF biosensor for rapid and label-free detection