Skip to main content

News about Scitation

In December 2016 Scitation will launch with a new design, enhanced navigation and a much improved user experience.

To ensure a smooth transition, from today, we are temporarily stopping new account registration and single article purchases. If you already have an account you can continue to use the site as normal.

For help or more information please visit our FAQs.

banner image
No data available.
Please log in to see this content.
You have no subscription access to this content.
No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.
/content/aip/journal/bmf/1/2/10.1063/1.2732208
1.
1.S. J. Lee and S. Y. Lee, Appl. Microbiol. Biotechnol. 64, 289 (2004).
http://dx.doi.org/10.1007/s00253-003-1515-0
2.
2.A. Manz, N. Graber, and H. M. Widmer, Sens. Actuators B 1, 244 (1990).
http://dx.doi.org/10.1016/0925-4005(90)80209-I
3.
3.T. C. Kuo, D. M. Cannon, Jr., Y. Chen, J. J. Tulock, M. A. Shannon, J. V. Sweedler, and P. W. Bohn, Anal. Chem. 75, 1861 (2003).
http://dx.doi.org/10.1021/ac025958m
4.
4.J. J. Tulock, M. A. Shannon, P. W. Bohn, and J. V. Sweedler, Anal. Chem. 76, 6419 (2004).
http://dx.doi.org/10.1021/ac049601p
5.
5.J. M. Iannacone, J. A. Jakubowski, P. W. Bohn, and J. V. Sweedler, Electrophoresis 26, 4684 (2005).
http://dx.doi.org/10.1002/elps.200500498
6.
6.J. Han and H. G. Craighead, Science 288, 1026 (2000).
http://dx.doi.org/10.1126/science.288.5468.1026
7.
7.D. J. Harrison, K. Fluri, K. Seiler, Z. Fan, C. S. Effenhauser, and A. Manz, Science 261, 895 (1993).
http://dx.doi.org/10.1126/science.261.5123.895
8.
8.P. S. Dittrich, K. Tachikawa, and A. Manz, Anal. Chem. 78, 3887 (2006).
http://dx.doi.org/10.1021/ac0605602
9.
9.C. L. Rice and R. Whitehead, J. Phys. Chem. 69, 4017 (1965).
10.
10.B. R. Flachsbart, K. Wong, J. M. Iannacone, E. N. Abante, R. L. Vlach, P. A. Rauchfuss, P. W. Bohn, J. V. Sweedler, and M. A. Shannon, Lab Chip 6, 667 (2006).
http://dx.doi.org/10.1039/b514300d
11.
11.Y. C. Wang, A. L. Stevens, and J. Han, Anal. Chem. 77, 4293 (2005);
http://dx.doi.org/10.1021/ac050321z
11.Y. Zhang and A. T. Timperman, Analyst (Cambridge, U.K.) 128, 537 (2003).
http://dx.doi.org/10.1039/b300102d
12.
12.D. M. Cannon, Jr., T.-C. Kuo, J. V. Sweedler, and P. W. Bohn, Anal. Chem. 75, 2224 (2003).
http://dx.doi.org/10.1021/ac020629f
13.
13.T. C. Kuo, H. K. Kim, D. M. Cannon, Jr., M. A. Shannon, J. V. Sweedler, and P. W. Bohn, Angew. Chem., Int. Ed. 43, 1862 (2004).
http://dx.doi.org/10.1002/anie.200353279
14.
14.I. H. Chang, J. J. Tulock, J. Liu, W. S. Kim, D. M. Cannon, Jr., Y. Lu, and P. W. Bohn, Environ. Sci. Technol. 39, 3756 (2005).
http://dx.doi.org/10.1021/es040505f
15.
15.K. Fa, J. J. Tulock, J. V. Sweedler, and P. W. Bohn, J. Am. Chem. Soc. 127, 13928 (2005).
http://dx.doi.org/10.1021/ja052708p
16.
16.A. N. Chatterjee, D. M. Cannon, Jr., E. N. Gatimu, J. V. Sweedler, N. R. Aluru, and P. W. Bohn, J. Nanopart. Res. 7, 507 (2005).
http://dx.doi.org/10.1007/s11051-005-5133-x
17.
17.R. Qiao and N. R. Aluru, J. Chem. Phys. 118, 4692 (2003).
http://dx.doi.org/10.1063/1.1543140
18.
18.R. Qiao and N. R. Aluru, Phys. Rev. Lett. 92, 198301 (2004).
http://dx.doi.org/10.1103/PhysRevLett.92.198301
19.
19.N. Petsev Dimiter, J. Chem. Phys. 123, 244907 (2005).
http://dx.doi.org/10.1063/1.2135780
20.
20.L. Sun and R. M. Crooks, Langmuir 15, 738 (1999).
http://dx.doi.org/10.1021/la980871a
21.
21.C. C. Harrell, S. B. Lee, and C. R. Martin, Anal. Chem. 75, 6861 (2003).
http://dx.doi.org/10.1021/ac034602n
22.
22.P. Scopece, L. A. Baker, P. Ugo, and C. R. Martin, Nanotechnology 17, 3951 (2006).
http://dx.doi.org/10.1088/0957-4484/17/15/057
23.
23.D. M. Cannon, Jr., B. R. Flachsbart, M. A. Shannon, J. V. Sweedler, and P. W. Bohn, Appl. Phys. Lett. 85, 1241 (2004).
http://dx.doi.org/10.1063/1.1780605
24.
24.S. B. Lee and C. R. Martin, Chem. Mater. 13, 3236 (2001).
http://dx.doi.org/10.1021/cm0101071
25.
25.S. B. Lee and C. R. Martin, Anal. Chem. 73, 768 (2001).
http://dx.doi.org/10.1021/ac0008901
26.
26.Y. Ito, Y. S. Park, and Y. Imanishi, Langmuir 16, 5376 (2000).
http://dx.doi.org/10.1021/la991102+
27.
27.I. S. Lokuge and P. W. Bohn, Langmuir 21, 1979 (2005).
http://dx.doi.org/10.1021/la0400914
28.
28.I. Lokuge, X. Wang, and P. W. Bohn, Langmuir 23, 305 (2007).
http://dx.doi.org/10.1021/la060813m
29.
29.R. Karnik, K. Castelino, R. Fan, P. Yang, and A. Majumdar, Nano Lett. 5, 1638 (2005).
http://dx.doi.org/10.1021/nl050966e
30.
30.L. Sun, J. Dai, G. L. Baker, and M. L. Bruening, Chem. Mater. 18, 4033 (2006).
http://dx.doi.org/10.1021/cm060554m
31.
31.D. P. Wernette, C. B. Swearingen, D. M. Cropek, Y. Lu, J. V. Sweedler, and P. W. Bohn, Analyst (Cambridge, U.K.) 131, 41 (2006).
http://dx.doi.org/10.1039/b510071b
32.
32.T. Ito, L. Sun, M. A. Bevan, and R. M. Crooks, Langmuir 20, 6940 (2004).
http://dx.doi.org/10.1021/la049524t
33.
33.L. Q. Gu, O. Braha, S. Conlan, S. Cheley, and H. Bayley, Nature (London) 398, 686 (1999).
http://dx.doi.org/10.1038/19491
http://aip.metastore.ingenta.com/content/aip/journal/bmf/1/2/10.1063/1.2732208
Loading
/content/aip/journal/bmf/1/2/10.1063/1.2732208
Loading

Data & Media loading...

Loading

Article metrics loading...

/content/aip/journal/bmf/1/2/10.1063/1.2732208
2007-05-10
2016-12-03

Abstract

The extension of microfluidic devices to three dimensions requires innovative methods to interface fluidic layers. Externally controllable interconnects employing nanocapillary array membranes (NCAMs) have been exploited to produce hybrid three-dimensional fluidic architectures capable of performing linked sequential chemical manipulations of great power and utility. Because the solution Debye length, , is of the order of the channel diameter, , in the nanopores,fluidic transfer is controlled through applied bias, polarity and density of the immobile nanoporesurface charge,solution ionic strength and the impedance of the nanopore relative to the microfluidic channels. Analyte transport between vertically separated microchannels can be saturated at two stable transfer levels, corresponding to reverse and forward bias. These NCAM-mediated integrated microfluidic architectures have been used to achieve highly reproducible and tunable injections down to attoliter volumes, sample stacking for preconcentration, preparative analyte band collection from an electrophoretic separation, and an actively-tunable size-dependent transport in hybrid structures with grafted polymers displaying thermally-regulated swelling behavior. The synthetic elaboration of the nanopore interior has also been used to great effect to realize molecular separations of high efficiency. All of these manipulations depend critically on the transport properties of individual nanocapillaries, and the study of transport in single nanopores has recently attracted significant attention. Both computation and experimental studies have utilized single nanopores as test beds to understand the fundamental chemical and physical properties of chemistry and fluid flow at nanometer length scales.

Loading

Full text loading...

/deliver/fulltext/aip/journal/bmf/1/2/1.2732208.html;jsessionid=h2N25wEL5ZQhJYJ4SyCqyPdJ.x-aip-live-03?itemId=/content/aip/journal/bmf/1/2/10.1063/1.2732208&mimeType=html&fmt=ahah&containerItemId=content/aip/journal/bmf
true
true

Access Key

  • FFree Content
  • OAOpen Access Content
  • SSubscribed Content
  • TFree Trial Content
752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
/content/realmedia?fmt=ahah&adPositionList=
&advertTargetUrl=//oascentral.aip.org/RealMedia/ads/&sitePageValue=bmf.aip.org/1/2/10.1063/1.2732208&pageURL=http://scitation.aip.org/content/aip/journal/bmf/1/2/10.1063/1.2732208'
Right1,Right2,Right3,