Skip to main content

News about Scitation

In December 2016 Scitation will launch with a new design, enhanced navigation and a much improved user experience.

To ensure a smooth transition, from today, we are temporarily stopping new account registration and single article purchases. If you already have an account you can continue to use the site as normal.

For help or more information please visit our FAQs.

banner image
No data available.
Please log in to see this content.
You have no subscription access to this content.
No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.
1.M. Grumann, A. Geipel, L. Riegger, R. Zengerle, and J. Ducree, Lab Chip 5, 560 (2005).
2.P. Mitchell, Nat. Biotechnol. 19, 717 (2001).
3.R. L. Liu, M. A. Stremler, K. V. Sharp, M. G. Olsen, J. G. Santiago, R. J. Adrian, H. Are, D. Beebe, and J. Microelectromech. Syst. 9, 190 (2000).
4.V. Hessel, H. Lowe, and F. Schonfeld, Chem. Eng. Sci. 60, 2479 (2005).
5.G. G. Yaralioglu, I. O. Wygant, T. C. Marentis, and B. Khuri-Yakub, Anal. Chem. 76, 3694 (2004).
6.H. H. Bau, J. Zhong, and M. Yi, Sens. Actuators B 79, 207 (2001).
7.S. Jones and H. Aref, Phys. Fluids 31, 469 (1988).
8.M. H. Oddy, J. G. Santiago, and J. C. Mikkelsen, Anal. Chem. 73, 5822 (2001).
9.C. Erbacher, F. G. Bessoth, M. Busch, E. Verpoorte, and A. Manz, Mikrochim. Acta 131, 19 (1999).
10.F. G. Bessoth, A. J. deMello, and A. Manz, Anal. Commun. 36, 213 (1999).
11.J. B. Knight, A. Vishwanath, J. P. Brody, and R. H. Austin, Phys. Rev. Lett. 80, 3863 (1998).
12.A. D. Stroock, S. K. Dertinger, A. Ajdar, I. Mezic, H. A. Stone, and G. M. Whitesides, Science 295, 647 (2002).
13.T. J. Johnson, D. Ross, and L. E. Locascio, Anal. Chem. 74, 45 (2002).
14.H. Chen and J. -C . Meiners, Appl. Phys. Lett. 84, 2193 (2004).
15.A. Gunther, M. Jhinjhunwala, M. Thalmann, M. A. Schmidt, and K. F. Jensen, Langmuir 21, 1547 (2005).
16.A. Gunther, S. A. Khan, F. Trachsel, M. Thalmann, and K. F. Jensen, Lab Chip 4, 278 (2004).
17.H. Song, J. D. Tice, and R. F. Ismagilov, Angew. Chem., Int. Ed. 42, 768 (2003).
18.D. Gobby, P. Angeli, and A. Gavriilidis, J. Micromech. Microeng. 11, 126 (2001).
19.Y. Li, C. Dalton, H. Said, and K. V. S. Kaler, Proceeding of 3rd International Conference on Microchannels and Minichannels (Toronto, 2005), pp. 18.
20.S. Lee, H. Y. Lee, I. F. Lee, and C. Y. Tseng, Eur. J. Phys. 25, 331 (2004).
21.D. P. Schrum, C. T. Culbertson, S. C. Jacobson, and J. M. Ramsey, Anal. Chem. 71, 4173 (1999).

Data & Media loading...


Article metrics loading...



A focusing-based microfluidic mixer was studied. The micromixer utilizes the focusing process required for cytometry to reduce the diffusion distance of molecules to be mixed in order to facilitate the passive diffusion-controlled mixing process. It was found that both the high flow rate ratio of the sheath flow to the flows to be mixed and the low flow rate of the mixing fluids resulted in the short mixing length required within the microfluidic channel. It was shown that a complete mixing was achieved within a distance of 4 mm in the micromixer for the focused mixing fluids at a flow rate of and a flow rate ratio of the sheath flow to the flows to be mixed at 4:1. The mixer described here is simple and can be easily fabricated and controlled.


Full text loading...


Access Key

  • FFree Content
  • OAOpen Access Content
  • SSubscribed Content
  • TFree Trial Content
752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd