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Counting cells with a low-cost integrated microfluidics-waveguide sensor
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10.1063/1.3689857
/content/aip/journal/bmf/6/1/10.1063/1.3689857
http://aip.metastore.ingenta.com/content/aip/journal/bmf/6/1/10.1063/1.3689857
View: Figures

Figures

Image of FIG. 1.
FIG. 1.

(a) Schematic side view showing buried planar waveguide and the overlying microfluidic channel. Cells tagged with ferromagnetic beads are captured in the channel by the magnet. (b) Schematic of the optical setup. (c) Attenuation of transmitted light due to the number of metal-tagged cells above.

Image of FIG. 2.
FIG. 2.

Photocurrent shows decrease in signal upon serial addition of dilute ink. Four independent experiments are shown (each color represents an independent experiment) with a sigmoidal fit and the 95% confidence interval of the fit.

Image of FIG. 3.
FIG. 3.

(a) Composite micrograph of bead-tagged cells. Lymphocytes were labeled with CD45-AlexaFluor488 and tagged to ferromagnetic beads bearing anti-CD45 mAbs. Generally, each cell was tagged with one or more beads. (b) Photocurrent shows decrease in signal upon serial addition of dilute cells. Three experiments are shown (each color represents an independent experiment: red, green, blue) with a sigmoidal fit and the 95% confidence interval of the fit.

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/content/aip/journal/bmf/6/1/10.1063/1.3689857
2012-03-07
2014-04-25
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Counting cells with a low-cost integrated microfluidics-waveguide sensor
http://aip.metastore.ingenta.com/content/aip/journal/bmf/6/1/10.1063/1.3689857
10.1063/1.3689857
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