(a) Schematic of inertial particle focusing in a spiral microchannel. Particles that are randomly dispersed in the inlet region gradually form a well-ordered particle stream at a specific lateral position while migrating towards the outlets. (b)Photograph of the finished PDMS microfluidic device (the channel of which was filled with red ink for visualization). The inset (i) shows a microscope image of the channel cross-section.
(a) Fluorescent stream images illustrating the focusing behaviors of two particles in the outlet region at different flow rates. (b) Fluorescence intensity distributions across the channel width at flow rates where the instability occurs. (c)Lateral focusing position as a function of De; and gap between the main and minor focusing positions of 10 μm particles.
(a) Fluorescent stream images captured at various flow rates and the corresponding fluorescence intensities across the channel width, illustrating the interchange process of focusing positions of the two particles. Red solid arrow indicates the focusing position of 5 μm particles (the fluorescent streams of these particles are artificially pseudo-colored in red for enhanced contrast); green solid arrow indicates the main focusing position of 10 μm particles; and green hollow arrow indicates the minor position of 10 μm particles. (b) Focusing ratio as a function of De. The inset (i) shows the Gaussian fitting of the fluorescence intensity distribution of 10 μm particle stream at De = 4.31.
(a) Schematic of the developed five-stage process model. (b) Detailed stage distribution of the two particles.
(a) Schematic of inertial migration of zymosan bioparticles, fluorescent stream images captured near the bifurcated outlets and curves illustrating fluorescence intensity distribution across the channel width. The red line in the stream image of De = 0.86 indicates the specific position for measuring fluorescence intensity. (b) Dark-field microscope images of specimens sampled from the initial suspension and of collected samples after the enrichment operation at the flow rate of De = 12.08. The inset in sample three is an enlarged image showing the debris collected from the outer outlet. 2 μm polystyrene particles were artificially added into the initial suspension for size reference.
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