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Modeling the relaxation time of DNA confined in a nanochannel
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View: Figures


Image of FIG. 1.
FIG. 1.

Relaxation time (purple diamonds) obtained from Eq. (5) with and the WOSM compared to the experimental data of Reisner 37 (black triangles).

Image of FIG. 2.
FIG. 2.

(a) Fractional extension of DNA in a square nanochannel of size from Monte Carlo simulations (red circles) and from Reisner 37 (black triangles). Error bars for the simulation data are the standard error, and when not explicitly shown, the error is of order of the symbol size. Simulation parameters: (i.e., 1863 spheres). The same set of parameters is used throughout this work. (b) Same data plotted in dimensionless log-log form. The solid blue line is the prediction for the Odijk regime 10 with no free parameters. 14 The dashed line is the predicted slope for the proposed Gauss-de Gennes regime, 30 and the solid green line is the scaling with .

Image of FIG. 3.
FIG. 3.

Normalized chain friction (left panel, orange triangles) and normalized fluctuations in the mean span (right panel, blue squares) of the WOSM as a function of channel size.

Image of FIG. 4.
FIG. 4.

(a) Probability density function for the chain extension in the WOSM for different channel sizes as a function of fractional extension. The channel sizes shown are (from right to left in nm): 30, 36, 43, 52, 62, 74, 89, 106, 127, 152, 183, 219, 262, 314, 376, 450. (b) Normal probability plot of the 16 distributions. The solid black line indicates a normal distribution. The color scheme in both panels is the same.


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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Modeling the relaxation time of DNA confined in a nanochannel