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High repetition rate compact femtosecond laser: A powerful multiphoton tool for nanomedicine and nanobiotechnology
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10.1063/1.2745367
/content/aip/journal/jap/102/1/10.1063/1.2745367
http://aip.metastore.ingenta.com/content/aip/journal/jap/102/1/10.1063/1.2745367
View: Figures

Figures

Image of FIG. 1.
FIG. 1.

Scheme and image of the DermaInspect system with the Gigajet 20c laser. The laser beam is introduced in a galvoscanning unit, expanded, and deflected into a piezodriven high numerical aperture focusing optics.

Image of FIG. 2.
FIG. 2.

Schematic diagram and photograph of the galvoscanning microscope used for nanoprocessing.

Image of FIG. 3.
FIG. 3.

Two-photon autofluorescence image of Elodea leaf. No instantaneous photodamage was detectable.

Image of FIG. 4.
FIG. 4.

High-resolution multiphoton autofluorescence tomography of human skin. Eleven optical sections from different tissue depths out of a stack are depicted.

Image of FIG. 5.
FIG. 5.

Two-photon autofluorescence image of cells in the stratum spinosum at depth. Single mitochondria can be resolved.

Image of FIG. 6.
FIG. 6.

Laser cutting effects in Giemsa labeled human chromosomes and intact interphase blood cells (a) before laser processing and (b) after laser irradiation

Image of FIG. 7.
FIG. 7.

(a) Nanodissection and nanodrilling of labeled human chromosomes. An atomic force microscope (AFM) has been employed to measure the nanprocessing dimensions. (b) The lines indicate where the cuts and holes were measured. (c) Three-dimensional (3D) profile. (d) Examples of surface profiles of cuts and holes.

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/content/aip/journal/jap/102/1/10.1063/1.2745367
2007-07-02
2014-04-25
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: High (1GHz) repetition rate compact femtosecond laser: A powerful multiphoton tool for nanomedicine and nanobiotechnology
http://aip.metastore.ingenta.com/content/aip/journal/jap/102/1/10.1063/1.2745367
10.1063/1.2745367
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